超声引导下粗针活检术联合CD34免疫组化标记在隆突性皮肤纤维肉瘤诊断中的应用  

Application of ultrasound-guided core needle biopsy combined with CD34 immunohistochemistry labeling in the diagnosis of dermatofibrosarcoma protuberans

作　　者：魏莉[1] 孟宪杰[2] 洪蕾 王丽 WEI Li;MENG Xianjie;HONG Lei;WANG Li(Ultrasound Department of Shihezi People's Hospital,Shihezi,Xinjiang,832000,China;Pathology Department of Shihezi People's Hospital,Shihezi,Xinjiang,832000.China)

机构地区：[1]石河子市人民医院超声诊断科,新疆石河子832000 [2]石河子市人民医院病理科,新疆石河子832000

出　　处：《新疆医学》2024年第4期459-461,469,共4页Xinjiang Medical Journal

摘　　要：目的探讨超声引导下粗针活检术联合CD34在隆突性皮肤纤维肉瘤的诊断中的应用价值。方法回顾性分析于术前经超声引导下粗针活检术及CD34免疫组化标记诊断为隆突性皮肤纤维肉瘤的32例患者的病理资料与超声检查结果,并将其与手术后病理结果进行对比分析。结果32例患者中,30例患者于术前经超声引导下粗针活检术及CD34免疫组化标记诊断为隆突性皮肤纤维肉瘤,1例患者诊断为“倾向于隆突性皮肤纤维肉瘤”,另1例考虑“间叶源性肿瘤,不能除外纤维肉瘤”。术后病理结果提示31例患者为隆突性皮肤纤维肉瘤,1例患者为纤维肉瘤型皮肤纤维肉瘤。超声引导下粗针活检术联合CD34免疫组化标记诊断隆突性皮肤纤维肉瘤与术后病理结果的符合率为93.75%(30/31)。结论超声引导下粗针活检术联合CD34免疫组化标记诊断隆突性皮肤纤维肉瘤的准确性高,具有较大的临床应用价值。Objective To discuss the application value of ultrasound-guided core needle biopsy combined with CD34 immunohistochemistry in the diagnosis of dermatofibrosarcoma protuberans.Methods The pathological data and ultrasound examination results of 32 patients diagnosed with dermatofibrosarcoma protuberans through preoperative ultrasound-guided core needle biopsy and CD34 immunohistochemistry labeling were retrospectively analyzed,and compared the results with postoperative pathological results.Results Among the 32 patients,30 were diagnosed with dermatofibrosarcoma protuberans by ultrasound-guided coarse needle biopsy and CD34 immunohistochemical labeling before surgery,1 patient was diagnosed with“tendency towards protuberant skin fibrosarcoma”,and the other patient was considered“mesenchymal tumor,fibrosarcoma cannot be excluded”.The postoperative pathological results showed that 31 patients had dermatofibrosarcoma protuberans,and 1 patient had fibrosarcoma type fibrosarcoma.The coincidence rate between ultrasound-guided coarse needle biopsy combined with CD34 immunohistochemical labeling in the diagnosis of dermatofibrosarcoma protuberans and postoperative pathological results was 93.75%(30/31).Conclusion US-CNB combined with CD34 has a high coincidence rate in the diagnosis of dermatofibrosarcoma protuberans,which was of great clinical value.

关 键 词：隆突性皮肤纤维肉瘤 超声引导下粗针穿刺术 超声检查 CD34 病理 临床 

分 类 号：R445.1[医药卫生—影像医学与核医学]