同种异体肌腱处理技术的进展  

Progression in processing technique of tendon allograf

作　　者：张净宇 马荣星 王丽敏 胡永成[1] HANG Jing-yu;MA Rong-xing;WANG Li-min;HU Yong-cheng(Department of Bone Tumor and Soft Tissue Oncology,Tianjin Hospital,Tianjin 300211,China;Beijing Wonderful Medical BiomaterialsCompany,Beijing 101102,China)

机构地区：[1]天津市天津医院,天津300211 [2]北京威达峰医学生物材料有限责任公司,北京101102

出　　处：《中国矫形外科杂志》2024年第15期1398-1402,共5页Orthopedic Journal of China

基　　金：京津冀基础研究合作专项项目(编号:22JCZXJC00130)。

摘　　要：本综述全面总结了同种异体肌腱处理工艺的研究现状和前沿技术。同种异体肌腱处理流程为核心,系统总结了该领域的研究现状和前沿技术。肌腱移植成为肌腱损伤重建的主要手段之一。首先介绍了同种异体肌腱的应用背景和发展趋势,深入探讨了免疫原性与排斥反应相关的物理冷冻法和化学法,以及脱脂技术、脱细胞技术等处理方法。强调了同种异体肌腱处理工艺优化对于提高临床手术效果的重要性,为其运用于临床提供了科学依据和技术支持。This review comprehensively summarizes the current status and cutting-edge techniques of tendon allograft processing.The core of tendon allograft processing procedures is outlined,systematically summarizing the research status and advanced technologies in this field.Tendon allografting has become one of the main methods for tendon injury reconstruction.Initially,the application background and developmental trends of tendons allograft are introduced,followed by an in-depth discussion on physical cryopreservation and chemical methods related to immunogenicity and rejection reactions,as well as processing techniques such as defatting and decellularization.Emphasis is placed on the importance of optimizing tendon allograft processing techniques to enhance clinical surgical outcomes,providing scientific evidence and technological support for its clinical application.

关 键 词：同种异体肌腱 免疫原性 处理技术 

分 类 号：R687[医药卫生—骨科学]