Join the club:YIPF3 and YIPF4 act as Golgiphagy receptors  

作　　者：Xiaoli Ma Hong Zhang 

机构地区：[1]National Laboratory of Biomacromolecules,New Cornerstone Science Laboratory,Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China [2]College of Life Sciences,University of Chinese Academy of Sciences,Beijing 100049,China

出　　处：《Life Metabolism》2024年第1期7-9,共3页生命代谢（英文）

摘　　要：Autophagic degradation of membrane-bound organelles such as the endoplasmic reticulum(ER),mitochondria,and peroxisomes is mediated by a family of receptors.In a recent study,Hickey et al.revealed that autophagy triggered by nutrient stress,previously thought to degrade bulk cytoplasmic contents,prioritizes the ER and Golgi as cargoes for degradation.They further demonstrated that Yip1 domain family member 3(YIPF3)and YIPF4 act as receptors to mediate the delivery of Golgi to the lysosomes for Golgi remodelling during nutrient stress and also neuronal differentiation.

关 键 词：PF4 reticulum 

分 类 号：Q251[生物学—细胞生物学]