偏热环境下气流运动对人体免疫球蛋白浓度的影响  

Effects of the airflow on human immunoglobulin concentrations in a warm environment

作　　者：王刚[1] 韩立彬 梁士民 薛令辉 王丽丽 Wang Gang;Han Libin;Liang Shimin;Xue Linghui;Wang Lili(Qingdao University of Technology,School of Environmental and Municipal Engineering,Shandong Engineering Research Center of Healthy Environment and Low-Carbon Energy,Qingdao 266520,China)

机构地区：[1]青岛理工大学环境与市政工程学院,健康环境与低碳能源山东省工程研究中心,青岛266520

出　　处：《航天医学与医学工程》2024年第4期222-227,244,共7页Space Medicine & Medical Engineering

基　　金：国家自然科学基金(52108080)。

摘　　要：目的探讨偏热环境下气流刺激对人体免疫球蛋白浓度的影响,并讨论分析免疫球蛋白浓度与主观问卷结果间的相关性。方法在人工气候实验室通过改造后的吹风装置营造不同模式的动态气流,测量12名受试者暴露在不同气流环境中的S-IgA和S-IgE浓度变化,并同时调研受试者的TSV、TCV、吹风感、气流满意度和气流不适症状投票。结果偏热环境中吹风后S-IgA浓度升高了56.3%,但后续的高风速工况反而导致S-IgA浓度降低了24.8%;S-IgA和S-IgE均在TSV中性时浓度最高,S-IgA浓度在舒适时比不舒适时高176%;S-IgA浓度与平均风速呈倒“U”型关系,且当平均风速为1.0 m/s时,S-IgA浓度最高。结论气流运动对S-IgA浓度存在显著影响,但对S-IgE浓度的影响不大,偏热环境中较为舒适的吹风有利于提高S-IgA浓度,增强呼吸系统免疫力,但风速过高引起的强吹风感以及不满意的气流环境会导致S-IgA浓度降低。Objective To explore the effects of airflow stimuli on human immunoglobulin concentrations in a warm environment,and to discuss and analyze the correlations between immunoglobulin concentrations and subjective questionnaires results.Methods Dynamic airflow of different modes was created by a modified wind blowing device in the climate chamber.Then the changes of S-IgA and S-IgE concentrations of 12 subjects exposed to different airflow environments were measured,during which the TSV,TCV,draught perception,satisfaction with the airflow,and airflow discomfort symptom polling of the subjects were investigated.Results The S-IgA concentration increased by 56.3%after blowing in the warm environment,but the subsequent high air speed condition resulted in a decrease of S-IgA concentration by 24.8%.Both S-IgA and S-IgE had the highest concentrations when the TSV was neutral,and the S-IgA concentration was 176%higher under comfortable conditions than that under uncomfortable conditions.The S-IgA concentration showed an inverted"U"-shaped relationship with the average wind speed,and the highest S-IgA concentration was observed when the mean air speed was 1.0 m/s.Conclusion Dynamic airflow has a significant effect on S-IgA concentration but little effect on S-IgE concentration.Comfortable airflow in a warm environment could benefit the S-IgA concentration elevation thus the respiratory immunity.However,a strong draught perception caused by high wind speeds and an unsatisfactory airflow environment can lead to lower S-IgA concentrations.

关 键 词：偏热环境 气流运动 S-IGA S-IgE 呼吸免疫 

分 类 号：R852[医药卫生—航空、航天与航海医学]