溃疡性结肠炎“缓解-复发”临界态专家诊疗共识意见  

Expert consensus on diagnosis and treatment of the "remission-recurrence" critical state of ulcerative colitis

作　　者：世界中医药学会联合会消化病专业委员会 赵鲁卿[2] 张声生[2] 杨洪军[3] Specialty Committee of Digestive System Disease of World Federation of Chinese Medicine Societies

机构地区：[1]不详 [2]首都医科大学附属北京中医医院 [3]中国中医科学院

出　　处：《中国中西医结合消化杂志》2024年第8期652-659,共8页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

基　　金：国家自然科学基金重点专项(No:82341235);国家自然科学基金面上项目(No:82174304);北京市科委首都特色项目(No:Z181100001718218)。

摘　　要：溃疡性结肠炎是消化系统的重大疑难疾病,严重影响患者的生活质量。近年来,由于生活方式及环境因素的转变,UC的全球发病率呈上升趋势,目前最新治疗虽然在溃疡性结肠炎的诱导缓解等方面取得了一定的进展,但在如何阻断或延缓本病的复发方面,依然没有取得重大突破,是当今临床治疗中的瓶颈和重要挑战。为了有效应对这一挑战,本共识创新提出了溃疡性结肠炎“缓解-复发”临界态的新概念,并对其特征进行了深入探讨。共识体现了具有中国特色的中西医结合的医学特点,主要内容包括溃疡性结肠炎的病因和发病机制、临界态的实用识别方法、主要关键中医证候的诊断、临界态中医药干预和调摄策略等。本共识结合了最新的研究成果,旨在为临床医生提供全面的指导,以便更有效地管理溃疡性结肠炎患者,降低疾病复发率,从而改善患者的整体预后。Ulcerative colitis(UC) is a significant and challenging disease in the digestive system that severely affects the quality of life for patients. In recent years, due to changes in lifestyle and environmental factors, the global incidence of UC has been on the rise. Although the latest treatments have made certain progress in inducing remission of UC, there has been no significant breakthrough in preventing or delaying the recurrence of the disease, which remains a bottleneck and a major challenge in clinical treatment today. To effectively address this challenge, this consensus innovatively proposes the new concept of the "remission-recurrence" critical state in UC and conducts an in-depth discussion of its characteristics. The consensus reflects the medical characteristics of the integration of Chinese and Western medicine with Chinese characteristics, mainly including the etiology and pathogenesis of UC, practical identification methods for the critical state, diagnosis of the main key Chinese medicine syndromes, and intervention and regulation strategies for traditional Chinese medicine in the critical state. Combining the latest research findings, this consensus aims to provide comprehensive guidance for clinicians to more effectively manage patients with UC, reduce the rate of disease relapse, and thereby improve the overall prognosis of patients.

关 键 词：溃疡性结肠炎 “缓解-复发”临界态 中医 诊断 治疗 共识 

分 类 号：R259[医药卫生—中西医结合]