博落回生物碱的提取工艺及其在动物养殖中的研究进展  

Research progress on extraction technology of Macleaya microcarpa alkaloids and its application in animal breeding

作　　者：钱玺丞 张稳[1] 罗杰[1] 贾长青 梁浩[1] 郁建生[1] QIAN Xicheng;ZHANG Wen;LUO Jie;JIA Changqing;LIANG Hao;YU Jiansheng(Key Open Laboratory of Traditional Chinese Veterinary Medicine,Tongren Polytechnic College,Tongren 554300,China)

机构地区：[1]铜仁职业技术学院国家民委中兽药重点开放实验室,贵州铜仁554300

出　　处：《黑龙江畜牧兽医》2024年第15期19-24,共6页Heilongjiang Animal Science And veterinary Medicine

基　　金：贵州省科技计划项目(黔科合支撑[2022]一般141);贵州省教育厅高校科技创新团队项目(黔教技[2023]097);铜仁市科技计划项目(铜市科研[2021]34);武陵山民族药研发创新及综合利用技术人才团队项目(tzkpt[2022]188-09)。

摘　　要：博落回生物碱是中兽药博落回的功能性成分,其提取工艺多种多样,利用传统的酸提碱沉法即可得到粗提物,工艺简单易于工业化生产,而液膜法、内部沸腾法、超声波提取技术、超临界流体萃取技术、亚临界流体萃取技术等新方法、新技术结合萃取法、结晶法、色谱法等分离纯化技术的应用,对提高中药提取率、活性成分提取率及获取高纯度有效成分等具有显著作用和优势。以血根碱和白屈菜红碱为主要成分开发的新中兽药和药物饲料添加剂产品在改善消化道健康、增强机体免疫力、促进生长、提高生产性能及替代抗生素改善动物健康等方面效果显著。文章综述了博落回生物碱的提取、分离纯化、生物活性及其在动物养殖中的应用进展,以期为博落回生物碱的深层次开发及进一步应用提供参考。Macleaya cordata alkaloids are the functional components of Chinese veterinary medicine Macleaya cordata,and their extraction process is various.The crude extract can be obtained by traditional acid extraction and alkali sedimentation method,which is simple and easy for industrial production.The application of new methods such as liquid membrane method,internal boiling method,ultrasonic extraction technology,supercritical fluid extraction technology,subcritical fluid extraction technology,and separation and purification technologies such as new technology combined extraction method,crystallization method,chromatography,etc.,has significant effects and advantages on improving the extraction rate and the extraction rate of active ingredients and obtaining high-purity active ingredients.The new Chinese veterinary drugs and medicinal feed additives developed with sanguinarine and chelidonine as the main components have remarkable effects on improving digestive tract health,enhancing body immunity,promoting growth,improving production performance and replacing antibiotics to improve animal health.In this paper,the extraction,purification,bioactivity and application of Macleaya cordata in animal breeding were reviewed in order to provide reference for deep development and further research and application of Macleaya cordata.

关 键 词：博落回 生物碱 提取工艺 生物活性 动物养殖 

分 类 号：S816.2[农业科学—饲料科学] R282.4[农业科学—畜牧学]