经皮左心耳封堵术的争议与探索  

Percutaneous Left Atrial Appendage Occlusion:Controversy and Exploration

作　　者：杨婧[1] 尤玲[1] 张艳[1] 张光明[1] 耿雪[1] 邢航航 谢瑞芹 YANG Jing;YOU Ling;ZHANG Yan;ZHANG Guangming;GENG Xue;XING Hanghang;XIE Ruiqin(Division of Cardiology,The Second Hospital of Hebei Medical University,Shijiazhuang 050000,China)

机构地区：[1]河北医科大学第二医院心内一科,石家庄050000

出　　处：《中国循环杂志》2024年第8期828-832,共5页Chinese Circulation Journal

基　　金：河北省自然科学基金(H2020206081)。

摘　　要：经皮左心耳封堵术(LAAO)已成为不能耐受口服抗凝药的非瓣膜性心房颤动患者脑卒中预防的一种替代治疗策略。多项研究证实,LAAO预防血栓栓塞事件具有良好的安全性及有效性。随着国内外专家对LAAO逐渐认可,该技术在心房颤动患者脑卒中预防方面得到了迅速发展,但仍有许多问题值得深入探究。本文从LAAO对左心房结构和功能的影响、最佳的LAAO策略以及LAAO术后最佳的抗栓治疗等方面进行综述。Percutaneous left atrial appendage occlusion(LAAO)has emerged as a non-pharmacologic alternative for stroke prevention in non-valvular atrial fibrillation patients.Multiple clinical studies have confirmed that LAAO is safe and effective in the prevention of thromboembolic events for atrial fibrillation patients.With the worldwide recognition of LAAO,it obtains rapid development in the prevention of cardioembolic stroke,but there are still questionable issues worthy of further exploration.The aim of this review is to discuss the effect of LAAO on atrial structure and function,the optimal strategy of LAAO and the best antithrombotic treatment after LAAO.

关 键 词：心房颤动 左心耳封堵术 左心房功能 封堵策略 抗栓治疗 

分 类 号：R54[医药卫生—心血管疾病]