医疗机构阿片类药物滥用现状、监测及监管建议  

Current situation,monitoring and regulatory recommendations for opioid abuse in medical institutions

作　　者：司成 凌俐 张海霞[3] 吴晓燕[3] 葛卫红[1,3] Si Cheng;Ling Li;Zhang Haixia;Wu Xiaoyan;Ge Weihong(Nanjing Drum Tower Hospital Clinical College,Nanjing University of Chinese Medicine,Nanjing 210008,China;Nanjing Drum Tower Hospital,Clinical College,Nanjing Medical University,Nanjing 210008,China;Department of Pharmacy,Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School,Nanjing 210008,China)

机构地区：[1]南京中医药大学鼓楼临床医学院,南京210008 [2]南京医科大学鼓楼临床医学院,南京210008 [3]南京大学医学院附属鼓楼医院药学部,南京210008

出　　处：《药物不良反应杂志》2024年第8期493-498,共6页Adverse Drug Reactions Journal

基　　金：南京市卫生科技发展专项(ZKX23020);南京大学中国医院改革发展研究院课题(NDYGN2023001)。

摘　　要：阿片类药物存在药物滥用的风险。随着阿片类药物在慢性疼痛治疗中的广泛使用,医疗机构开展阿片类药物滥用风险监测具有重要意义。本文介绍了阿片类药物滥用相关术语,总结了阿片类药物滥用现状及医疗机构药物滥用的风险,介绍了阿片类药物滥用风险监测工具以及药物治疗的停药问题,并就医疗机构阿片类药物滥用存在的问题提出了建议,为医疗机构建立适合国情的药物滥用警戒体系、促进阿片类药物用药安全提供参考。There is a risk of drug abuse associated with opioid drugs.With the widespread use of opioid drugs in chronic pain,it is of great significance to carry out risk monitoring of opioid drug abuse in medical institutions.This article introduces the relevant terms of opioid drug abuse,summarizes the current situation of opioid drug abuse and the risk situation of drug abuse in medical institutions,introduces the moni-toring tools for opioid drug abuse risks and the issue of discontinuation of drug treatment,and puts forward suggestions for the problems on opioid drug abuse in medical institutions,providing a reference for medical institutions to establish a pharmacovigilance system for drug abuse suitable for national conditions and promote the safe use of opioid drugs.

关 键 词：镇痛药 阿片类 疼痛 药物滥用 阿片类药物使用障碍 风险监测 

分 类 号：R95[医药卫生—药学]