基于体外实验的光电容积脉搏波信号检测及脉率特性  

Photoplethysmography Pulse Wave Signal Detection and Pulse Rate Characteristics Based on an in vitro Experiment

作　　者：何卫俊 刘雍陶 刘登吉 尹凯 贺缨 迟青卓 母立众 HE Weijun;LIU Yongtao;LIU Dengji;YIN Kai;HE Ying;CHI Qingzhuo;MU Lizhong(Key Laboratory of Ocean Energy Utilization and Energy Conservation of Ministry of Education,School of Energy and Power Engineering,Dalian University of Technology,Dalian 116024,Liaoning,China)

机构地区：[1]大连理工大学能源与动力学院,海洋能源利用与节能教育部重点实验室,辽宁大连116024

出　　处：《医用生物力学》2024年第4期712-717,共6页Journal of Medical Biomechanics

基　　金：中央高校基本科研业务费(DUT22YG206);国家自然科学基金项目(51976026)。

摘　　要：目的借助体外循环实验系统的可控参数优势考察血流参数变化对脉率特性的影响。方法建立一套搭载腕部体外模型的人体循环系统,通过分别改变心率、腕部流量、压力和系统顺应性等参数,从腕部模型中获取光电容积脉搏波信号,并提取脉率变异性的时域和频域指标。结果心率、压力和系统顺应性的改变会引起脉搏波形状的改变,但能够表明脉率变异性的时域指标NN50、PNN50数值为0,其他指标以及频域指标都处在极低值范畴。结论在未有心率变异性时,心率、腕部流量、血压和系统顺应性等血流动力学变化未产生明显的脉率变异性。本研究可为临床在更便利的腕部采集设备加持下开展更多脉率变异性和心率变异性研究提供参考。Objective To investigate the influence of changes in blood flow parameters on pulse rate characteristics by taking the advantage of controllable parameters in an experimental cardiopulmonary bypass system.Methods A set of human circulatory system equipped with an in vitro wrist model was established.By changing parameters such as the heart rate,wrist flow,pressure,and system compliance,a photoplethysmography pulse wave signal was obtained from the wrist model,and the time-and frequency-domain indices of pulse rate variability were extracted.Results Changes in heart rate,pressure,and system compliance caused a change in pulse shape,but the time domain indices NN50 and PNN50,which indicate pulse rate variability,were zero,and the other indices and frequency domain indices were in the very low value category.Conclusions In the absence of heart rate variability,hemodynamic changes in heart rate,wrist flow,blood pressure,and system compliance did not produce significant pulse rate variability.This study can provide a reference for studies on pulse rate variability and heart rate using more convenient wrist acquisition equipment.

关 键 词：脉率变异性 光电容积脉搏波 循环系统体外模型 血流动力学 

分 类 号：R318.01[医药卫生—生物医学工程]