棉籽中胺鲜酯和甲哌鎓残留的HPLC/MS/MS法检测及其膳食摄入风险评估  

Determination of DA-6 and Mepiquat Chloride Residue in Cottonseed by HPLC-MS/MS and Dietary Intake Risk Assessment

作　　者：臧娅磊 周娟[2] 陈贺 张可松 郑先福[3] Zang Yalei;Zhang Kesong;Zhou Juan;Chen He;Zheng Xianfu(Zhengzhou Zheng Shi Chemical Co.,Ltd./Henan Crop Chemical Control Engineering Research Center,Zhengzhou Henan 450002,China;Institute of Quality and Safety for Agro-products,Henan Academy of Agricultural Sciences,Zhengzhou Henan 450002,China;Henan Agricultural University,Zhengzhou Henan 450002,China)

机构地区：[1]郑州郑氏化工产品有限公司/河南省作物化控工程技术研究中心,河南郑州450002 [2]河南省农业科学院农产品质量安全研究所,河南郑州450002 [3]河南农业大学,河南郑州450000

出　　处：《农药科学与管理》2024年第8期43-48,共6页Pesticide Science and Administration

摘　　要：建立了胺鲜酯和甲哌鎓在棉籽中残留的HPLC/MS/MS法检测方法,并对棉籽中胺鲜酯和甲哌鎓残留量进行了膳食摄入风险评估。胺鲜酯平均回收率分别为88%~97%,相对标准偏差分别为6.6%~7.3%;甲哌鎓平均回收率分别为84%~92%,相对标准偏差分别为3.6%~9.4%;棉籽中胺鲜酯和甲哌鎓的最低检测浓度均为0.01 mg/kg。按本试验设计进行施药,不同采收间隔期棉籽中胺鲜酯和甲哌鎓的残留量分别为≤0.01 mg/kg和≤0.48 mg/kg。胺鲜酯的普通人群国家估计每日摄入量是0.047 mg,占日允许摄入量的3.3%左右;甲哌鎓的国家估算每日摄入量是0.33 mg,占日允许摄入量的2.7%。认为对一般人群健康不会产生不可接受的风险。An analytical method for determining the residues of DA-6 and Mepiquat chloride in cottonseed was established by HPLC/MS/MS,along with a dietary intake risk assessment of cottonseed.The average recoveries of DA-6 and Mepiquat in cottonseed were shown to range from 88%to 97%and 84%to 92%,respectively,with relative standard deviations(RSD)of 6.86%to 7.3%and 3.6%to 9.4%,respectively.The limits of quantification(LOQ)were 0.01 mg/kg for cottonseed.Based on the designed application in this study,the terminal residues of DA-6 and Mepiquat chloride at different harvest interval in cottonseed were lower than 0.01mg/kg and 0.48mg/kg,respectively.The national estimated daily intake for the general population was 0.047mg for DA-6,accounting for 3.3%of the ADI.For Mepiquat chloride,it was 0.33mg,accounting for 2.7%of the ADI.It is concluded that the potential health risk induced by DA-6 and Mepiquat chloride was determined to be insignificant based on supervised residue trial data.

关 键 词：胺鲜酯 甲哌鎓 棉籽 残留检测 膳食摄入评估 

分 类 号：S482.8[农业科学—农药学] S481.8[农业科学—植物保护]