经导管主动脉瓣置换术后生物瓣功能障碍的研究进展  

Bioprosthetic Valve Dysfunction After Transcatheter Aortic Valve Replacement

作　　者：杨振宇 方伟 任何 胡健强 马文帅 王秋和 李妍 YANG Zhenyu;FANG Wei;REN He;HU Jianqiang;MA Wenshuai;WANG Qiuhe;LI Yan(Department of Cardiology,Tangdu Hospital,Air Force Military Medical University,Xi’an 710038,Shaanxi,China)

机构地区：[1]空军军医大学唐都医院心血管内科,陕西西安710038

出　　处：《心血管病学进展》2024年第8期690-696,共7页Advances in Cardiovascular Diseases

基　　金：国家自然科学基金(82070385)。

摘　　要：经导管主动脉瓣置换术(TAVR)已成为治疗主动脉瓣狭窄的重要介入手段,得益于材料技术的进步与操作经验的积累,TAVR已广泛运用于外科手术中高风险的患者,并逐渐向年轻、低风险患者拓展。生物瓣作为TAVR的核心材料,其功能障碍可能影响手术效果和患者的生活质量。现对生物瓣功能障碍的诊断评估、危险因素、临床预后和相关研究成果进行总结,旨在为预防和减轻生物瓣功能障碍、提高生物瓣的耐久性提供参考。Transcatheter aortic valve replacement(TAVR)is an important intervention for patients with aortic stenosis.Thanks to the advancement of material technology and the accumulation of operational experience,TAVR has been widely used in high-risk patients and is gradually expanding to younger and low-risk patients.As the core material of TAVR,bioprosthetic valve dysfunction may reduce treatment efficacy and patient quality of life.This review comprehensively summarizes the diagnosis and prognosis of bioprosthetic valve dysfunction,providing reference for preventing and reducing biological valve dysfunction and improving the durability of bioprosthetic valve.

关 键 词：主动脉瓣狭窄 经导管主动脉瓣置换术 生物瓣功能障碍 耐久性 

分 类 号：R654.2[医药卫生—外科学]