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作 者:徐敬端[1] 高鹏飞 赵盼盼 陈婷 Xu Jing-duan;Gao Peng-fei;Zhao Pan-pan;Chen Ting(Department of Respiratory Medicine,The First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471003,Henan,China)
机构地区:[1]河南科技大学第一附属医院呼吸内科,河南洛阳471003
出 处:《四川生理科学杂志》2024年第8期1668-1670,1793,共4页
基 金:河南省医学科技攻关计划项目(编号:LHGJ20220671)。
摘 要:目的:探究胸腔积液穿刺引流术后患者应用基于营养风险评估下的营养支持措施的干预效果及对免疫功能、营养学指标的影响。方法:选取我科2020年3月至2023年3月期间80例胸腔积液穿刺引流术后患者,依据抽签法分组。对照组40例给予常规护理,观察组40例增加基于营养风险评估下的营养支持。4 w后,对比两组患者血清营养学指标:白蛋白(Albumin,ALB)、前白蛋白(Prealbumin,PA)、血红蛋白(Hemoglobin,Hb)、转铁蛋白(Transferrin,TRF);肺功能:第1s用力呼气量(Forced expiratory volume,FEV1)、肺活量(Vital capacity,VC)、每分钟最大通气量(Maximum ventilation per minute,MVV)、用力肺活量(Forced vital capacity,FVC);免疫功能指标:CD3^(+)、CD4^(+)、CD8^(+)、CD4^(+)/CD8^(+)水平。结果:术后观察组CD8^(+)水平低于对照组,TRF、ALB、Hb、VC、FEV1、FVC、CD3^(+)、MVV、CD4^(+)、PA、CD4^(+)/CD8^(+)水平高于对照组,差异有统计学意义(P<0.05)。结论:基于营养风险评估下的营养支持对胸腔积液穿刺引流术后患者干预,可有效提高患者免疫功能、营养状态,促进肺功能恢复。Objective:To explore the effect of nutritional support measures based on nutritional risk assessment on immune function and nutritional indexes in patients after pleural effusion puncture and drainage.Methods:A total of 80 patients with pleural effusion after puncture and drainage from March 2020 to March 2023 were selected and divided into groups according to the drawing method.The control group(40 cases)received routine nursing,and the observation group(40 cases)received nutritional support based on nutritional risk assessment.After 4 weeks,serum nutritional indexes of Albumin(ALB),Prealbumin(PA),Hemoglobin(Hb),and Transferrin(TRF)were compared between the two groups.Lung function:1s Forced expiratory volume(FEV1),Vital capacity(VC),Maximum ventilation per minute,(MVV),Forced vital capacity(FVC);Indicators of immune function:CD3^(+),CD4^(+),CD8^(+),CD4^(+)/CD8^(+)levels.Results:The level of CD8^(+)in the observation group was lower than that in the control group,and the levels of TRF,ALB,Hb,VC,FEV1,FVC,CD3^(+),MVV,CD4^(+),PA,CD4^(+)/CD8^(+)were higher than those in the control group,with statistical significance(P<0.05).Conclusion:Nutritional support based on nutritional risk assessment can effectively improve the immune function and nutritional status of patients after pleural effusion puncture and drainage,and promote the recovery of lung function.
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