卡孕栓辅助卡贝缩宫素应用于剖宫产产后出血的预防效果及安全性比较  

Comparison of the preventive effect and safety of carprost suppository combined with carbetocin on postpartum hemorrhage after cesarean section

作　　者：彭如情 Peng Ru-qing(Guixi Women and Children's Hospital Obstetrics and Gynecology,Guixi 335400,Jiangxi,China)

机构地区：[1]贵溪市妇女儿童医院妇产科,江西贵溪335400

出　　处：《四川生理科学杂志》2024年第8期1858-1860,共3页

摘　　要：目的:探究卡孕栓辅助卡贝缩宫素结合应用于剖宫产产后出血中的预防效果以及安全性。方法:回顾性分析2022年1月至2023年12月期间,本院收治的剖宫产孕妇共计75例,根据产妇接受的干预方式的不同,将上述研究对象划分为观察组(n=42)、对照组(n=33);其中对照组患者接受卡贝缩宫素干预,观察组在对照组的基础之上联合卡孕栓辅助干预,干预结束后记录并比较两组研究对象产后出血情况、出血时间、恶露持续时间以及不良反应发生率。结果:结果显示,观察组患者在产后2 h以及产后24 h的出血量均低于对照组(P<0.05);观察组患者接受干预后的止血时间以及恶露持续时间均低于对照组(P<0.05);与此同时,两组研究对象接受相应干预后,不良反应发生率无明显差异(P>0.05)。结论:卡孕栓辅助卡贝缩宫素能够有效预防剖宫产产后出血、降低出血量并缩短出血时间,且不增加不良反应发生率,具有较高的应用价值。Objective:To explore the preventive effect and safety of carprost suppository combined with carbetocin in postpartum hemorrhage of cesarean section.Methods:A retrospective analysis was conducted on 75 cesarean section pregnant women admitted to our hospital from January 2022 to December 2023.Based on the different intervention methods received by the pregnant women,the study subjects were divided into an observation group(n=42)and a control group(n=33);The patients in the control group were treated with carbetocin intervention,and the observation group was combined with carprost suppository on the basis of the control group.After the intervention,the postpartum bleeding situation,bleeding time,lochia duration,and incidence of adverse reactions of the two groups of study subjects were recorded and compared.Results:The comparative results showed that the bleeding volume of the observation group patients at 2 hours postpartum and 24 hours postpartum was lower than that of the control group(P<0.05);The hemostasis time and lochia duration of the observation group patients after intervention were lower than those of the control group(P<0.05);At the same time,there was no significant difference in the incidence of adverse reactions between the two groups of study subjects after receiving corresponding interventions(P>0.05).Conclusion:Carboprost suppository assisted carbetocin intervention can effectively prevent postpartum hemorrhage after cesarean section,reduce the amount of bleeding and shorten the time of bleeding,without increasing the incidence of adverse reactions,and has high application value.

关 键 词：卡贝缩宫素 卡孕栓 剖宫产产后出血 预防效果 不良反应发生率 

分 类 号：R719.8[医药卫生—妇产科学]