中药复方治疗痰瘀互结型冠心病的研究进展  

Research progress of Chinese herbal compound in treatment of coronary heart disease with syndrome of intermingled phlegm and blood stasis

作　　者：艾纯颖 米金霞 谢燕 AI Chunying;MI Jinxia;XIE Yan(School of Public Health,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)

机构地区：[1]上海中医药大学公共健康学院,上海201203

出　　处：《上海中医药大学学报》2024年第4期92-101,112,共11页Academic Journal of Shanghai University of Traditional Chinese Medicine

基　　金：上海市生物医药科技支撑专项项目(22S21900900)。

摘　　要：冠心病是指由于冠状动脉粥样硬化使管腔狭窄、痉挛或阻塞导致心肌缺血、缺氧或坏死而引发的心脏病。随着人们生活习惯的改变,冠心病发病率逐年升高,严重危害人类健康。该病属中医学“胸痹”“心痛”范畴,并认为当属本虚标实,且“阳微阴弦”是冠心病的经典阐释。研究表明,痰浊与血瘀为冠心病的重要致病因素,同时也是病理产物,痰瘀互结作为冠心病基本病机贯穿疾病始终,是冠心病主要证型,临床研究也证实中药复方对冠心病痰瘀互结证具有确切疗效。通过查阅近年相关文献并进行归纳总结与分析,从经典方剂、经验方、中药复方制剂、中药复方与西药合用、中药复方联合其他中医疗法等方面对中药复方治疗痰瘀互结型冠心病的研究现状作一综述,以期为治疗冠心病痰瘀互结证的临床选方用药提供新的思路和有益参考。Coronary heart disease(CHD)is a heart condition triggered by myocardial ischemia,hypoxia or necrosis due to lumen stenosis,spasm or blockage caused by coronary atherosclerosis.With the change of people's living habits,the incidence of CHD is increasing year by year,seriously endangering human health.According to Chinese traditional medicine,CHD is deficiency in interior and excess in exterior,which belongs to the category of"chest impediment"and"heartache",and"Yang weakness and Yin excess"is the classic interpretation of CHD.Studies have shown that phlegm and blood stasis are not only the important pathogenic factors of CHD,but also the pathological products.Intermingled phlegm and blood stasis,as the basic pathogenesis throughout the disease,is the main syndrome of CHD.Clinical studies have confirmed that Chinese herbal compound has definite efficacy on CHD with sydrome of intermingled phlegm and blood stasis.This paper consulted the relevant literatures in recent years and summarized and analyzed,it reviewed the research progress of Chinese herbal compound on the treatment of CHD with syndrome of intermingled phlegm and blood stasis from the aspects of classical prescriptions,empirical prescriptions,Chinese herbal compound preparation,combination of Chinese herbal compound and western medicine,and Chinese herbal compound combined with other traditional Chinese medicine therapies,in order to provide some new ideas and beneficial references for the clinical selection of prescription and medication in the treatment of CHD with syndrome of intermingled phlegm and blood stasis.

关 键 词：冠心病 痰瘀互结 经典方剂 经验方 中药复方制剂 

分 类 号：R259[医药卫生—中西医结合]