青钱柳醇提浸膏挥发性香气成分及其热裂解产物的GC-MS分析研究  

Volatile aromatic components and pyrolytic products in ethanol extracts of Cyclocarya paliurus by GC-MS

作　　者：张兴贵 方泗杨 陈蕊 熊怡乐 董卉林 张健[3] 秦艳华[2] 殷志琦 ZHANG Xinggui;FANG Siyang;CHEN Rui;XIONG Yile;DONG Huilin;ZHANG Jian;QIN Yanhua;YIN Zhiqi(Department of TCMs Pharmaceuticals,School of Traditional Chinese Pharmacy,China Pharmaceutical University,Nanjing 211198;China Tobacco Jiangsu Industrial Co.,Ltd.,Nanjing 210019;Jiangsu Provincial Academy of Traditional Chinese Medicine,Nanjing 210028,China)

机构地区：[1]中国药科大学中药学院中药制药系,南京211198 [2]江苏中烟工业有限责任公司,南京210019 [3]江苏省中医药研究院转化医学实验室,南京210028

出　　处：《中国药科大学学报》2024年第4期493-503,共11页Journal of China Pharmaceutical University

基　　金：江苏中烟工业有限责任公司科技项目(No.H202204)。

摘　　要：为研究青钱柳浸膏作为添加剂应用于卷烟的可行性,采用气相-离子迁移谱(GC-IMS)分析挥发性香气成分,通过单热重-气相色谱-质谱联用技术(TGA-GC/MS)模拟燃烧过程,分析青钱柳浸膏在氮气环境中的裂解产物,并对产物可能的裂解机制进行合理推测。结果表明:醛类、醇类、酮类为青钱柳浸膏的主要挥发性香气成分,占总香气成分的62.28%。在不同温度条件下,青钱柳浸膏裂解产物差异较大,在200℃、360℃、440℃共鉴定出79种化合物,其中24种致香成分对卷烟风格具有重要作用,包括醛、酮、醇、酚、呋喃、芳香族化合物和其他一些天然香气物质,其中含量较多的酚类化合物主要是由含有类似愈创木酚单元和丁香酚单元结构的化合物通过侧链的断裂、脱甲基化、脱甲氧基化、脱水等形成,呋喃及呋喃衍生物主要由糖类或糖苷类化合物通过断裂糖苷键和脱水形成。In order to investigate the feasibility of the extract from Cyclocarya paliurus as an additive in cigarettes,the volatile aromatic components were analyzed by gas chromatography-ion mobility spectrometry(GC-IMS),and C.paliurus extract was pyrolyzed to simulate cigarette smoking by TGA-GC/MS.The cracking products of C.paliurus were analyzed in a nitrogen environment,and the possible cracking mechanism of the products was reasonably speculated.The results showed that aldehydes,alcohols,and ketones were the primary volatile aroma components of the C.paliurus extract,comprising 62.28%of the total aroma components.The cracking products of C.paliurus extract varied greatly under different temperature conditions.A total of 79 compounds were identified at 200,360,and 440℃,among which 24 aromatic components were clearly identified as having significant effects on cigarette style,including aldehydes,ketones,alcohols,phenols,furans,benzene series,and other natural aromatic substances.Among them,phenols containing a high concentration are mainly formed by compounds containing the structure of guaiacol unit and eugenol unit by side chain cleavage,demethylation,demethoxylation,dehydration,etc.Furan and its derivatives are mainly formed by glycosides or glycoside compounds by breaking glucoside bonds and dehydration.

关 键 词：青钱柳 浸膏 挥发性香气成分 气相色谱/质谱联用 裂解产物 裂解机制 

分 类 号：R917[医药卫生—药物分析学]