胎儿髓鞘发育的定量MRI研究进展  

Progress of Quantitative MRI Research on Fetal Myelin Development

作　　者：洪子涵 杨梦莹 李金芹 张彦玲 王卓 陈兵[1] HONG Zihan;YANG Mengying;LI Jinqin;ZHANG Yanling;WANG Zhuo;CHEN Bing(Department of Radiology,General Hospital of Ningxia Medical University,Yinchuan 750004,China)

机构地区：[1]宁夏医科大学总医院放射科,宁夏银川750004 [2]宁夏医科大学总医院妇产中心功能检查部,宁夏银川750004

出　　处：《中国医学影像学杂志》2024年第8期855-859,共5页Chinese Journal of Medical Imaging

基　　金：宁夏回族自治区科技惠民计划专项(2022CMG03051);宁医大总院〔2023〕394号2022年新入职硕士人才培养项目。

摘　　要：人类髓鞘形成始于胎儿发育的第5个月,出生后持续,髓鞘发育在建立和维持大脑内的信息传导、协调和交流方面起着关键作用。因此,髓鞘发育的产前定量评估十分重要。近年来已经开发并实施了许多用于髓鞘成像的MRI技术,关于胎儿髓鞘发育的MRI定量评估也越来越受关注。本文讨论了胎儿中枢神经系统髓鞘发育的结构和功能变化,并就胎儿MRI定量成像的研究进展及未来期望进行综述。Human myelination begins in the fifth month of fetal development and continues after birth.Myelin development plays a key role in establishing and maintaining information conduction,coordination and communication within the brain,so prenatal quantitative assessment of myelin development is important.In recent years,many MRI techniques for myelin imaging have been developed and implemented,and quantitative MRI assessment of fetal myelin development has received increasing attention.In this review,we discuss the known structural and functional changes in the development of the myelin sheath of the fetal central nervous system,and review the research progress and future expectations of quantitative fetal MRI imaging.

关 键 词：髓鞘 中枢神经系统 磁共振成像 胎儿 生长发育 综述 

分 类 号：R714.5[医药卫生—妇产科学] R445.2[医药卫生—临床医学]