胃息肉中医证型、病理类型与幽门螺杆菌感染的相关性研究  

Study on Correlation Between Traditional Chinese Medicine Syndrome Type,Pathological Types and Helicobacter Pylori Infection of Gastric Polyps

作　　者：盛好 王新国 马兴婷 王家平[2] SHENG Hao;WANG Xinguo;MA Xingting;WANG Jiaping(Department of Spleen and Stomach Diseases,Traditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region,Urumqi 830017,China;Department of Traditional Chinese Medicine,The Fifth Affiliated Hospital of Xinjiang Medical University,Urumqi 830011,China)

机构地区：[1]新疆维吾尔自治区中医医院脾胃病科,新疆乌鲁木齐830017 [2]新疆医科大学第五附属医院中医科,新疆乌鲁木齐830011

出　　处：《山东中医杂志》2024年第9期970-976,共7页Shandong Journal of Traditional Chinese Medicine

基　　金：新疆医科大学附属中医医院院级课题(编号:ZYY202010)。

摘　　要：目的:探讨胃息肉的中医证型、病理类型与幽门螺杆菌(Hp)感染之间的相关性。方法:选取胃息肉患者500例为研究对象,收集患者的中医证候和病理诊断结果,对患者的中医证型、临床病理类型和Hp感染结果进行统计分析,研究中医证型、病理类型与Hp感染之间的关系,探讨Hp感染与二者的相关性。结果:500例胃息肉患者男女比例为1∶1.6,高发病年龄为50~<60岁,Hp检出率为16.4%;病理类型以胃底腺息肉(43.6%)和炎性息肉(40.6%)最为多见,其次为增生性息肉(15.0%)、腺瘤样息肉(0.8%),Hp阳性率以炎性息肉最高(57.3%),且与其他病理类型阳性率比较差异有统计学意义(P<0.001);中医证型以脾胃虚弱证(47.6%)最为多见,其余依次为脾胃湿热证(24.6%)、肝胃不和证(13.4%)、胃络瘀阻证(7.4%)、痰湿中阻证(7.0%),Hp阳性率以脾胃虚弱证最高(51.2%),且与其余中医证型阳性率比较差异有统计学意义(P<0.001);不同病理类型的胃息肉患者中医证型均以脾胃虚弱证多见,其中增生性息肉、胃底腺息肉、炎性息肉脾胃虚弱证与其余中医证型比较,差异有统计学意义(P<0.001)。结论:胃底腺息肉和炎性息肉为胃息肉常见病理类型,脾胃虚弱证为最常见中医证型;胃息肉合并Hp感染以炎性息肉多见,多为脾胃虚弱证,提示脾胃虚弱为胃息肉主要病机,且与Hp感染密切相关。Objective:To investigate the correlation between the traditional Chinese medicine(TCM)syndrome and pathological types of gastric polyps and Helicobacter pylori(Hp)infection.Methods:A total of 500 patients with gastric polyps were selected as the research subjects,the TCM syndrome and pathological diagnosis results of the patients were collected,and the TCM syndrome types,clinicopathological types and Hp infection results of the patients were statistically analyzed,the relationship between TCM syndrome types and pathological types and Hp infection was studied,and the correlation between Hp infection and the two was explored.Results:The ratio of male to female in 500 patients with gastric polyps was 1∶1.6,and the high incidence age was 50~<60 years old.The detection rate of Hp was 16.4%.The most common pathological types were gastric fundus gland polyps(43.6%)and inflammatory polyp(40.6%),which were followed by hyperplastic polyp(15.0%)and adenomatous polyp(0.8%).The positive rate of Hp was highest in inflammatory polyp(57.3%),and the positive rate was statistically significant compared with other pathological types(P<0.001).Spleen and stomach weakness syndrome(47.6%)was the most common type of TCM syndrome,which was followed by spleen and stomach dampness-heat syndrome(24.6%),liver and stomach disharmony syndrome(13.4%),stomach stasis syndrome(7.4%)and phlegm-dampness-obstruction syndrome(7.0%).The positive rate of Hp was highest in spleen and stomach weakness syndrome(51.2%).There was statistically significant difference between the positive rate and other TCM syndrome types(P<0.001).Spleen and stomach weakness was the most common syndrome in patients with different pathological types of gastric polyps,and the difference between hyperplastic polyps,fundus glandular polyps,inflammatory polyps and other syn‐dromes was statistically significant(P<0.001).Conclusions:Gastric fundus glandular polyp and inflammatory polyp are common pathological types of gastric polyp,and spleen and stomach weakness syndrome is the

关 键 词：胃息肉 中医证型 病理类型 幽门螺杆菌 脾胃虚弱 炎性息肉 胃底腺息肉 

分 类 号：R259.739[医药卫生—中西医结合]