中医调节气道神经源性炎症反应治疗慢性咳嗽概述  

An Overview of Traditional Chinese Medicine Regulating Airway Neurogenic Inflammatory Response in Treatment of Chronic Cough

作　　者：刘向娜 冯延朵 王瑞兆 张世卿[2] LIU Xiangna;FENG Yanduo;WANG Ruizhao;ZHANG Shiqing(Henan University of Chinese Medicine,Zhengzhou 450003,China;The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450003,China)

机构地区：[1]河南中医药大学,河南郑州450003 [2]河南中医药大学第一附属医院,河南郑州450003

出　　处：《山东中医杂志》2024年第9期1039-1045,共7页Shandong Journal of Traditional Chinese Medicine

基　　金：国家中医药传承创新中心科研专项课题(编号:2023ZXZX1030);河南省中医药科学研究专项课题(编号:2019ZY2016)。

摘　　要：慢性咳嗽指以咳嗽为主症或唯一症状且病程持续8周以上的一种病证,咳嗽迁延不愈不仅会影响正常生活,严重者可出现支气管破裂、纵隔气肿等并发症。近年来中医药在慢性咳嗽的治疗过程中发挥了重要作用,探索中医预防和治疗慢性咳嗽的机制研究较多,研究表明中医疗法可通过减少炎症因子分泌、抑制神经肽释放炎症介质,降低气道神经源性炎症反应改善咳嗽症状。为明确中医治疗慢性咳嗽的优势,特归纳了其治疗慢性咳嗽的几个关键环节,指出了中医内治法、推拿、针刺、艾灸、拔罐、耳穴压贴等疗法通过调节气道神经源性炎症反应治疗慢性咳嗽的机制。参考文献62篇。Chronic cough refers to a disease with cough as the main or the only symptom and the course of the disease lasts more than 8 weeks.Prolonged cough will not only affect the normal life,but also lead to bronchial rupture,mediastinal emphysema and other complications in severe cases.In recent years,traditional Chinese medicine has played an important role in the treatment of chronic cough.Many studies have explored the mechanism of traditional Chinese medicine in preventing and treating chronic cough.Studies have shown that traditional Chinese medicine can relieve cough symptoms by reducing the secretion of inflammatory factors and inhibiting the release of inflammatory mediators by neuropeptides to reducing airway neurogenic inflammatory response.In order to clarify the advantages of traditional Chinese medicine in the treatment of chronic cough,this paper summarizes several key links in the treatment of chronic cough,and points out the mechanism of traditional Chinese medicine internal treatment,massage,acupuncture,moxibustion,cupping,ear point pressure and other therapies in regulating airway neurogenic inflammatory response to treat chronic cough.There are 62 references.

关 键 词：慢性咳嗽 炎症因子 神经肽 气道神经源性炎症反应 

分 类 号：R256.11[医药卫生—中医内科学]