中医外治法调节“脑-肠轴”治疗功能性便秘研究进展  

Research Progress on Traditional Chinese Medicine External Therapy in Treatment of Functional Constipation by Adjusting“Brain-Gut Axis”

作　　者：李岫学 韩孟珂 戴明[2] LI Xiuxue;HAN Mengke;DAI Ming(Shanghai University of Traditional Chinese Medicine,Shanghai 200120,China;Longhua Hospital Shanghai University of Traditional Chinese Medicine,Shanghai 200030,China)

机构地区：[1]上海中医药大学,上海200120 [2]上海中医药大学附属龙华医院,上海200030

出　　处：《山东中医杂志》2024年第9期1046-1052,共7页Shandong Journal of Traditional Chinese Medicine

基　　金：上海中医药大学附属龙华医院“龙医健康行”项目(编号:YW.006.022)。

摘　　要：“脑-肠轴”失衡被认为是功能性便秘(FC)的重要发病机制,其主要包括脑肠神经调控异常和脑肠肽分泌异常。以针灸为代表的中医外治法可通过调控脑肠轴的神经功能,改善脑肠肽含量,发挥对FC的治疗作用。查阅国内外文献,对包括针刺、灸法、穴位贴敷、穴位埋线、耳穴压丸、推拿在内的中医外治法调控“脑-肠互动”治疗FC的相关作用效果,即调节脑肠神经、恢复脑肠肽水平、减轻便秘症状、改善心理状况等展开综述,并对现有研究存在的不足进行探讨,以期为后续中医外治法治疗FC的临床和实验研究提供思路和参考。参考文献61篇。Imbalance of the“brain-gut axis”is considered to be an important pathogenesis of functional constipation(FC),it mainly includes abnormal brain-gut neuromodulation and abnormal secretion of brain-gut peptides.External therapy of traditional Chinese medicine,such as acupuncture and moxibustion,can play a therapeutic role on FC by regulating the neural function of the brain-gut axis and regulating the content of brain-gut peptides.By referring to domestic and foreign literatures,this paper summarizes the effects of external therapies of traditional Chinese medicine(TCM),including acupuncture,moxibustion,acupoint application,acupoint embedding,auricular acupressure and massage in regulating the“brain-gut interaction”in the treatment of FC.That is,TCM external therapies can regulate cerebral and intestinal nerves,restore the level of cerebral and intestinal peptides,alleviate the symptoms of constipation,and improve the psychological situation.Meanwhile,the shortcomings of the existing studies are discussed in order to provide ideas and references for the subsequent clinical and experimental research on TCM external therapies in the treatment of FC.There are 61 references.

关 键 词：脑-肠轴 功能性便秘 中医外治法 脑肠神经 脑肠肽 脑-肠互动 

分 类 号：R244[医药卫生—针灸推拿学] R256.35[医药卫生—中医临床基础]