The association of diet quality and physical activity with cardiovascular disease and mortality in 85,545 older Australians:A longitudinal study  

作　　者：Ding Ding Joe Van Buskirk Stephanie Partridge Philip Clare Edward Giovannucci Adrian Bauman Nicole Freene Robyn Gallagher Binh Nguyen 

机构地区：[1]Sydney School of Public Health,Faculty of Medicine and Health,the University of Sydney,Camperdown,NSW 2006,Australia [2]Charles Perkins Centre,the University of Sydney,Camperdown,NSW 2006,Australia [3]Sydney Local Health District,Camperdown,NSW 2050,Australia [4]School of Health Sciences,Faculty of Medicine and Health,the University of Sydney,Camperdown,NSW 2006,Australia [5]National Drug and Alcohol Research Centre,UNSW Sydney,Sydney,NSW 2052,Australia [6]Departments of Nutrition and Epidemiology,Harvard T.H.Chan School of Public Health,Boston,MA 02115,USA [7]Faculty of Health,University of Canberra,Canberra,ACT 2617,Australia [8]Susan Wakil School of Nursing and Midwifery,the University of Sydney,Camperdown,NSW 2050,Australia

出　　处：《Journal of Sport and Health Science》2024年第6期841-850,共10页运动与健康科学（英文）

基　　金：the Heart Foundation Australia(#101234,#101583);an Emerging Leader Fellowship from the National Health and Medical Research Council(2009254);an Early-Mid Career Researcher Grant under the New South Wales Cardiovascular Research Capacity Program.

摘　　要：Background:A quality diet and an active lifestyle are both important cornerstones of cardiovascular disease(CVD)prevention.However,despite their interlinked effects on metabolic health,the 2 behaviors are rarely considered jointly,particularly within the context of CVD prevention.We examined the independent,interactive,and joint associations of diet and physical activity with CVD hospitalization,CVD mortality,and all-cause mortality.Methods:CVD-free Australian participants aged 4574 years(n=85,545)reported physical activity,diet,sociodemographic,and lifestyle characteristics at baseline(20062009)and follow-up(20122015),and data were linked to hospitalization and death registries(03/31/2019 for CVD hospitalization and all-cause mortality and 12/08/2017 for CVD mortality).Diet quality was categorized as low,medium,and high based on meeting dietary recommendations.Physical activity was operationalized as(a)total moderate-to-vigorous physical activity(MVPA)as per guidelines,and(b)the composition of MVPA as the ratio of vigorous-intensity physical activity(VPA)to total MVPA.We used a left-truncated cause-specific Cox proportional hazards model using time-varying covariates.Results:During a median of 10.7 years of follow-up,6576 participants were admitted to the hospital for CVD and 6581 died from all causes(876 from CVD during 9.3 years).A high-quality diet was associated with a 17%lower risk of all-cause mortality than a low-quality diet,and the highest MVPA category(compared with the lowest)was associated with a 44%and 48%lower risk of CVD and all-cause mortality,respectively.Multiplicative interactions between diet and physical activity were non-significant.For all outcomes,the lowest risk combinations involved a high-quality diet and the highest MVPA categories.Accounting for total MVPA,some VPA was associated with further risk reduction of CVD hospitalization and all-cause mortality.Conclusion:For CVD prevention and longevity,one should adhere to both a healthy diet and an active lifestyle and incorporate some VP

关 键 词：DIET Physical activity Cardiovascular disease MORTALITY Cohort studies 

分 类 号：G804.2[文化科学—运动人体科学] R54[文化科学—体育学]