肥胖2型糖尿病痰热互结证患者治疗中小陷胸汤合防己茯苓汤的应用效果  

Application Effect of Small Trap Thoracic Decoction Combined with Fangji Poria Decoction in the Treatment of Obese Patients with Type 2 Diabetes Mellitus with Intermingled Phlegm-heat Syndrome

作　　者：孙师钢 汪勤 SUN Shigang;WANG Qin(Department of TCM Internal Medicine,Jilin Provincial Rehabilitation Center for Persons with Disabilities,Changchun 130000,Jilin,China;Innovation Practice Center,Changchun University of Chinese Medicine,Changchun 130000,Jilin,China)

机构地区：[1]吉林省残疾人康复中心中医内科,吉林长春130000 [2]长春中医药大学创新实践中心,吉林长春130000

出　　处：《糖尿病新世界》2024年第10期106-108,112,共4页Diabetes New World

摘　　要：目的探究肥胖2型糖尿病(type 2 diabetes mellitus,T2DM)痰热互结证患者应用小陷胸汤合防己茯苓汤的效果。方法选取2022年2月—2024年2月在吉林省残疾人康复中心就诊的112例肥胖T2DM痰热互结证患者作为研究对象,以不同的治疗方法将其分为对照组(n=56,采用二甲双胍治疗)、研究组(n=56,采用二甲双胍与小陷胸汤合防己茯苓汤联合治疗)。比较两组肥胖指标(体重、体重指数、腰围)、糖代谢指标(空腹血糖、餐后2 h血糖、糖化血红蛋白)及中医症候(包括腹部胀大、形体肥胖、胸闷脘痞、口干口渴、饮水量多、心烦口苦、小便色黄、大便干结)积分改善情况。结果治疗90 d后,研究组体重、体重指数、腰围均低于对照组,差异有统计学意义(P均<0.05)。治疗90 d后,研究组糖代谢指标、中医症候积分均低于对照组,差异有统计学意义(P均<0.05)。结论小陷胸汤合防己茯苓汤应用于肥胖T2DM痰热互结证患者治疗中,可减轻其体重,糖代谢控制效果显著,并改善中医症候积分。Objective To explore the effect of Small Trap Thoracic Decoction combined with Fangji Poria Decoction on obese patients with type 2 diabetes mellitus(T2DM)with intermingled phlegm-heat syndrome.Methods From Feb-ruary 2022 to February 2024,a total of 112 obese T2DM patients with intermingled phlegm-heat syndrome who were treated in the Jilin Provincial Rehabilitation Center for Persons with Disabilities were selected as the research objects.They were divided into control group(n=56,treated with metformin)and study group(n=56,treated with metformin combined with Small Trap Thoracic Decoction combined with Fangji Poria Decoction)by different treatment methods.The improvement of obesity indexes(body weight,body mass index,waist circumference),glucose metabolism indexes(fasting plasma glucose,2-hour postprandial plasma glucose,glycated hemoglobin A1c)and traditional Chinese medi-cine(TCM)symptoms(including abdominal distension,physical obesity,chest tightness and abdominal distension,dry mouth and thirst,more water intake,upset and bitter taste,yellow urine color,dry stool)score were compared between the two groups.Results After 90 days of treatment,the body weight,body mass index and waist circumference of the study group were lower than those of the control group,and the differences were statistically significant(all P<0.05).After 90 days of treatment,the glucose metabolism indexes and TCM symptom score of the study group were lower than those of the control group,and the differences were statistically significant(all P<0.05).Conclusion The applica-tion of Small Trap Thoracic Decoction combined with Fangji Poria Decoction in the treatment of obese T2DM patients with intermingled phlegm-heat syndrome can reduce their weight,significantly control glucose metabolism,and im-prove TCM syndrome scores.

关 键 词：2型糖尿病 痰热互结证 小陷胸汤合防己茯苓汤 糖代谢 中医症候积分 

分 类 号：R587.1[医药卫生—内分泌]