多波长激光联合曲安奈德在糖尿病黄斑水肿患者中的效果研究  

Effect of Multi Wavelength Laser Combined with Triamcinolone Aceton⁃ide on Macular Edema in Patients with Diabetes Mellitus

作　　者：耿祥娥 GENG Xiang'e(Department of Ophthalmology,Zhucheng People's Hospital,Weifang 262200,Shandong,China)

机构地区：[1]诸城市人民医院眼科,山东潍坊262200

出　　处：《糖尿病新世界》2024年第10期165-167,171,共4页Diabetes New World

摘　　要：目的探讨多波长激光联合曲安奈德在糖尿病黄斑水肿患者中的应用效果。方法选取2021年6月—2023年9月诸城市人民医院收治的94例糖尿病黄斑水肿患者,按治疗方法不同分为两组,各47例。两组均给予内界膜剥除术治疗,对照组采用曲安奈德治疗,观察组在对照组基础上联合多波长激光治疗,两组均完成12周干预,比较两组血糖水平、视网膜厚度、最佳矫正视力、眼压水平及不良反应发生率。结果干预后,两组患者血糖水平均降低,且观察组低于对照组,差异有统计学意义(P均<0.05)。干预后,观察组视网膜厚度及眼压低于对照组,最佳矫正视力高于对照组,差异有统计学意义(P均<0.05)。观察组不良反应发生率低于对照组,但差异无统计学意义(P>0.05)。结论多波长激光联合曲安奈德用于糖尿病黄斑水肿患者中,能降低视网膜厚度水平,提升其最佳矫正视力,有助于降低患者血糖水平,未增加不良反应发生率。Objective To investigate the effect of multi-wavelength laser combined with triamcinolone acetonide in patients with diabetic macular edema.Methods A total of 94 patients with diabetic macular edema admitted to Zhucheng People's Hospital from June 2021 to September 2023 were selected and divided into two groups with 47 cases each according to different treatment methods.Both groups were treated with internal boundary membrane strip-ping,the control group was treated with triamcinolone and the observation group was treated with multi-wavelength la-ser therapy on the basis of the control group.Both groups completed 12 weeks of intervention,and the blood glucose level,retinal thickness,optimal corrected visual acuity,IOP level and incidence of adverse reactions were compared between the two groups.Results After intervention,the blood glucose levels of the two groups decreased,and those in the observation group were lower than the control group,the differences were statistically significant(all P<0.05).Af-ter intervention,the retinal thickness and IOP in the observation group were lower than those in the control group,and the best corrected visual acuity was higher than that in the control group,and the differences were statistically signifi-cant(all P<0.05).The incidence of adrerse reactions in the observation group was lower than that in the control group,but the difference was not statistically significant(P>0.05).Conclusion Multi-wavelength laser combined with triamcinolone acetonide in patients with diabetic macular edema can reduce the level of retinal thickness,improve their best corrected visual acuity,help to reduce the blood glucose level of patients,and do not increase the incidence of adverse reactions.

关 键 词：多波长激光 曲安奈德 糖尿病黄斑水肿 血糖水平 最佳矫正视力 视网膜厚度 眼压水平 

分 类 号：R587[医药卫生—内分泌]