经尿道前列腺电切术在中晚期前列腺癌中的应用价值  

The Value of Transurethral Electrolysis of the Prostate in Intermediate and Advanced Prostate Cancer

作　　者：胡振宇 解福军 孙燕滨 HU Zhenyu;JIE Fujun;SUN Yanbin(Department of Urology,Jiaozhou Hospital of East Hospital Affiliated to Tongji University,Qingdao 266300,Shandong,China;Department of Gastroenterology,Qingdao Jiaozhou Central Hospital,Qingdao 266300,Shandong,China)

机构地区：[1]同济大学附属东方医院胶州医院泌尿外科,山东青岛266300 [2]青岛市胶州中心医院消化内科,山东青岛266300

出　　处：《系统医学》2024年第13期130-133,共4页Systems Medicine

摘　　要：目的探究中晚期前列腺癌实施经尿道前列腺电切术的价值。方法回顾性选取同济大学附属东方医院胶州医院于2022年6月—2023年6月收治的68例中晚期前列腺癌患者的临床资料,按照治疗方式的不同分为分析组和对照组,每组34例。对照组采用常规内分泌治疗,分析组基于对照组实施经尿道前列腺电切术。比较两组患者的5年生存率、最大尿流率、残余尿量、前列腺特异性抗原、国际前列腺症状评分(Interna-tional Prostate Symptom Score,IPSS)。结果两组患者的5年生存率比较,差异无统计学意义(P>0.05);分析组最大尿流率、残余尿量、前列腺特异性抗原显著较对照组优,差异有统计学意义(P均<0.05);分析组IPSS评分(2.61±1.20)分低于对照组的(5.36±1.49)分,差异有统计学意义(t=8.382,P<0.05)。结论经尿道前列腺电切术应用于中晚期前列腺癌患者,能够有效改善排尿困难症状,且不影响5年生存率,值得临床借鉴。Objective To explore the value of transurethral resection of prostate for advanced prostate cancer.Meth-ods Clinical data of 68 patients with advanced prostate cancer admitted to Jiaozhou Hospital,East Hospital Affiliated to Tongji University from June 2022 to June 2023 were retrospectively selected and divided into analysis group and control group according to different treatment methods,with 34 cases in each group.The control group received con-ventional endocrine therapy,and the analysis group received transurethral resection of prostate based on the control group.The 5-year survival rate,maximum urine flow rate,residual urine volume,prostate-specific antigen,and Inter-national Prostate Symptom Score(IPSS)of the two groups were compared.Results There was no significant difference in 5-year survival rate between the two groups(P>0.05).The maximum urine flow rate,residual urine volume and prostate-specific antigen in the analysis group were significantly better than those in the control group,the difference were statistically significant(all P<0.05).The IPSS score of the analysis group was 2.61±1.20,lower than 5.36±1.49 of the control group,and the difference was statistically significant(t=8.382,P<0.05).Conclusion Transurethral resec-tion of prostate can effectively improve the symptoms of dysuria in patients with advanced prostate cancer without af-fecting the 5-year survival rate,which is worthy of clinical reference.

关 键 词：中晚期前列腺癌 经尿道前列腺电切术 效果 

分 类 号：R699.8[医药卫生—泌尿科学]