超声与MRI认知融合在超声引导下经会阴前列腺癌穿刺活检的应用研究  

Application of ultrasound and MRI cognitive fusion in ultrasound-guided perineal biopsy of prostate cancer

作　　者：王影[1] 胡海峰[1] 刘慧临 周丹丹 张英慧 李璐 黄春鑫 WANG Ying;HU Haifeng;LIU Huilin;ZHOU Dandan;ZHANG Yinghui;LI Lu;HUANG Chunxin(Department of Ultrasonography,The Second Affiliated Hospital of Qiqihar Medical University,Qiqihar,Heilongjiang 161000,China)

机构地区：[1]齐齐哈尔医学院附属第二医院超声科,黑龙江齐齐哈尔161000

出　　处：《影像研究与医学应用》2024年第17期23-25,29,共4页Journal of Imaging Research and Medical Applications

基　　金：2020年度黑龙江省省属高等学校基本科研业务费科研项目“超声与MRI认知融合在超声引导下经会阴前列腺癌穿刺活检的应用研究”(2020-KYYWF-0031)。

摘　　要：目的:探讨超声与MRI认知融合在超声引导下经会阴前列腺癌穿刺活检中的临床价值。方法:选取2019年1月—2021年12月在齐齐哈尔医学院附属第二医院就诊,怀疑前列腺癌且前列腺特异性抗原>10 ng/mL的患者30例,均应用超声与MRI认知融合穿刺联合系统穿刺。对比分析不同方法对前列腺癌的总体检出率和临床显著前列腺癌的检出率等。结果:30例患者中经术中或术后病理结果诊断前列腺癌阳性28例,其中超声与MRI认知融合靶向联合系统穿刺检出阳性25例、阴性5例、误诊1例、漏诊4例;单一系统穿刺检出阳性21例、阴性9例、误诊1例、漏诊8例。超声与MRI认知融合穿刺联合系统穿刺方法检出前列腺癌阳性准确率、灵敏度高于单一系统穿刺方法,漏诊率低于单一系统穿刺方法;在前列腺癌的检出率方面两种不同的穿刺方法差异有统计学意义(χ^(2)=7.313,P=0.026);在临床显著前列腺癌的检出率方面两种不同的穿刺方法差异有统计学意义(χ^(2)=13.631,P=0.001);超声与MRI认知融合联合系统穿刺的单针阳性率高于单一系统穿刺,差异有统计学意义(P<0.05),两种穿刺方法的Gleason评分差异无统计学意义(P>0.05)。结论:超声与MRI认知融合联合系统穿刺活检对前列腺癌的诊断价值优于单一系统穿刺,能有效提高前列腺癌的检出率。Objective To investigate the clinical value of cognitive fusion of ultrasound and MRI in ultrasound-guided transperineal biopsy of prostate cancer(PCa).Methods A total of 30 patients with suspected prostate cancer and prostate specific antigen(PSA)greater than 10 ng/mL were selected from January 2019 to December 2021 in the second affiliated Hospital of Qiqihar Medical University.Ultrasound and MRI cognitive fusion targeting system puncture and single system puncture were used.The overall detection rate of prostate cancer and the detection rate of clinically significant prostate cancer(csPCa)by different methods were compared and analyzed.Results Among the 30 patients,28 cases were positive by pathology;of which 25 cases were positive,5 cases were negative,1 case was misdiagnosed and 4 cases were Missed diagnosis by ultrasound and MRI cognitive fusion targeting system;21 cases were positive,9 cases were negative,1 case was misdiagnosed and 8 cases were missed by single system puncture.The positive accuracy and sensitivity of ultrasound and MRI cognitive fusion targeting combined puncture method were higher than those of single system puncture method,but the missed diagnosis rate was lower than that of single system puncture method,and there was significant difference between the two different puncture methods in the detection rate of PCa.There was significant difference in the detection rate of csPCa between the two puncture methods(χ^(2)=13.631),and the positive rate of single needle in the combination of ultrasound and MRI cognitive fusion system was higher than that in the single system,but there was no significant difference in Gleason score between the two methods(P>0.05).Conclusion The diagnostic value of ultrasound and MRI cognitive fusion system puncture biopsy is better than that of single system puncture in the diagnosis of prostate cancer,and can effectively improve the detection rate of prostate cancer.

关 键 词：超声 MRI 认知融合 经会阴 穿刺 前列腺癌 

分 类 号：R445[医药卫生—影像医学与核医学]