彩色多普勒血流成像在早期糖尿病肾病中的诊断价值及肾动脉血流动力学指标分析  

Diagnostic value of color doppler flow imaging in early diabetes nephropathy and analysis of renal artery hemodynamic indexes

作　　者：王进 WANG Jin(Department of Ultrasound,Ningjin County Traditional Chinese Medicine Hospital,Dezhou,Shandong 253400,China)

机构地区：[1]宁津县中医院超声科,山东德州253400

出　　处：《影像研究与医学应用》2024年第17期46-48,共3页Journal of Imaging Research and Medical Applications

摘　　要：目的:探讨彩色多普勒血流成像(CDFI)在早期糖尿病肾病(DN)中的诊断价值及肾动脉血流动力学分析。方法:选取2021年1月—2024年1月宁津县中医院收治的92例疑似早期DN患者,均行CDFI检查,以肾穿刺活检或临床综合判断结果为金标准,统计DN检出情况及诊断价值,并以Kappa检验验证CDFI诊断DN与金标准的一致性;比较DN与非DN患者肾主动脉、叶间肾动脉血流收缩期峰值(PSV)、舒张末期血流速度(EDV)、阻力指数(RI)差异。结果:92例疑似患者经金标准确诊52例,其中CDFI检出51例,阳性率为98.08%;CDFI诊断早期DN的灵敏度为96.15%、特异度为97.50%、准确率为96.74%、阳性预测值为98.04%、阴性预测值为95.12%;Kappa检验显示,CDFI与金标准的Kappa值=0.934,一致性良好;DN组肾主动脉、叶间肾动脉PSV[(60.24±5.34)cm/s、(27.52±2.33)cm/s]、EDV[(17.15±1.37)cm/s、(9.25±1.14)cm/s]低于非DN组,RI[(0.69±0.12)、(0.65±0.11)]高于非DN组(P<0.05)。结论:CDFI在早期DN诊断中价值高,不仅可明确肾脏形态特征,还可检出肾动脉血流异常,利于早期识别肾脏病变,实现针对性治疗。Objective To investigate the diagnostic value of color Doppler flow imaging(CDFI)in early diabetes nephropathy(DN)and the analysis of renal artery hemodynamics.Methods A total of 92 patients with suspected early DN admitted to Ningjin County Hospital of Traditional Chinese Medicine from January 2021 to January 2024 were selected for CDFI examination.Renal puncture biopsy or clinical comprehensive judgment was used as the gold standard to analyze the detection and diagnostic value of DN,and Kappa test was used to verify the consistency of CDFI diagnosis of DN with the gold standard.The peak systolic velocity(PSV),end-diastolic velocity(EDV)and resistance index(RI)of renal aorta and interlobar renal artery were compared between DN and non-DN patients.Results Of 92 suspected patients,52 were confirmed by gold standard,of which 51 were detected by CDFI,with a positive rate of 98.08%.The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of CDFI were 96.15%,97.50%,96.74%,98.04%and 95.12%respectively.Kappa test showed that the Kappa value of CDFI and gold standard=0.934,which was very consistent.The PSV[(60.24±5.34)cm/s,(27.52±2.33)cm/s]and EDV[(17.15±1.37)cm/s,(9.25±1.14)cm/s]of renal aorta and interlobar renal artery in DN group were lower than those in non-DN group.RI[(0.69±0.12),(0.65±0.11)]were higher than those in the non-DN group(P<0.05).Conclusion CDFI has high value in the early diagnosis of DN.It can not only clarify the morphological characteristics of the kidney,but also detect abnormal renal artery blood flow,which is conducive to early identification of renal lesions and targeted treatment.

关 键 词：糖尿病肾病 彩色多普勒血流成像 肾动脉血流动力学 诊断价值 

分 类 号：R445.1[医药卫生—影像医学与核医学]