血栓弹力图在肛痈患者中的临床意义及病机探讨  

Clinical significance and pathogenesis of thromboelastography in patients with anal abscess

作　　者：张坤[1] 张海旋 ZHANG Kun;ZHANG Haixuan(Anorectal Department,Linyi Hospital of Traditional Chinese Medicine,Shandong,Linyi 276000,China;The First Clinical College of Shandong University of Traditional Chinese Medicine,Shandong,Jinan 250000,China)

机构地区：[1]山东省临沂市中医医院肛肠科,山东临沂276000 [2]山东中医药大学第一临床医学院,山东济南250000

出　　处：《中国医药科学》2024年第15期174-176,194,共4页China Medicine And Pharmacy

基　　金：山东省中医药科技项目(2019-0187)。

摘　　要：目的以血栓弹力图(TEG)作为客观化指标,探讨“瘀毒互结”病机在肛痈患者中的意义。方法收集2022年3—10月临沂市中医医院肛肠科肛痈及混合痔患者各100例,随机分为观察组和对照组,均进行血栓弹力图检测,计算R值、K值、MA值和Angle值,对比两组R值、K值、α角、Ma值和CI值,针对灵敏度绘制ROC图及ROC曲线,并计算曲线下面积(AUC)。结果血栓弹力图(TEG)各参数比较显示:观察组的R值、K值明显小于对照组,MA值、α角和CI明显大于对照组,均提示高凝状态;ROC曲线结果及AUC显示,R值、K值的诊断效能较高;α角、MA、CI具有一定的诊断效能。结论TEG可为肛痈的因毒致瘀病机提供客观依据,并可由此针对性制订治则治法。Objective To explore the significance of the pathogenesis of"stasis toxin"in the pathogenesis of anal abscess using thromboelastography(TEG)as an objective indicator.Methods From March 2022 to October 2022,a total of 100 patients with anal abscess and mixed hemorrhoids in the Anorectal Department,Linyi Hospital of Traditional Chinese Medicine were randomly divided into observation group and the control group,respectively.Thromboelastography was performed on both groups,and the R value,K value,MA value,and Angle value were calculated.The R value,K value,αangle,MA value and CI value of the two groups were compared,and the ROC diagram and ROC curve were drawn according to the sensitivity,and the area under the curve(AUC)was calculated.Results The comparison of the parameters of TEG showed that the R value and K value of the observation group were significantly lower than those of the control group,while the MA value,αangle and CI value were significantly higher than those of the control group,which indicated hypercoagulability.The results of ROC curve and AUC show that the diagnostic efficiency of R value and K value was high.αangle,MA and CI had certain diagnostic efficiency.Conclusion Thromboelastography(TEG)can provide an objective basis for the pathogenesis of anal abscess caused by stasis toxin,and can be used to develop targeted treatment principles and methods.

关 键 词：肛周脓肿 血栓弹力图 瘀毒 肛痈 

分 类 号：R269[医药卫生—中西医结合]