床旁纤维支气管镜治疗呼吸机相关性肺炎患者的应用效果分析  

Application Effect Analysis of Bedside Fiberoptic Bronchoscopy in the Treatment of Patients with Ventilator-associated Pneumonia

作　　者：邹秀丽 韦佳佳 王佐彬 ZOU Xiuli;WEI Jiajia;WANG Zuobin(Renhuai City People's Hospital,Zunyi 564500,Guizhou,China)

机构地区：[1]仁怀市人民医院,贵州遵义564500

出　　处：《中外医疗》2024年第19期53-56,81,共5页China & Foreign Medical Treatment

摘　　要：目的 评价床旁纤维支气管镜治疗呼吸机相关性肺炎的疗效。方法 随机选取2021年8月—2023年8月仁怀市人民医院收治的60例呼吸机相关性肺炎患者为研究对象。依据随机数字表法分为两组,各30例。对照组开展传统治疗,观察组开展床旁纤维支气管镜治疗。记录并比较两组治疗前后临床疗效、呼吸力学参数、炎性因子水平及临床症状评分。结果 治疗前,两组生活质量、炎性因子水平及临床症状评分对比,差异无统计学意义(P均>0.05)。治疗后,观察组治疗总有效率高于对照组、呼吸力学参数低于对照组,差异有统计学意义(P均<0.05)。观察组的C反应蛋白(7.13±1.01)mg/L、白细胞介素-6(98.41±11.12)pg/mL均低于对照组的(9.75±0.05)mg/L、(110.05±11.14)pg/mL,差异有统计学意义(t=14.191、4.050,P均<0.001)。观察组临床症状评分低于对照组,差异有统计学意义(P<0.05)。结论 开展床旁纤维支气管镜治疗后,有助于调节相关炎性因子水平,改善患者呼吸障碍情况,并促进其肺功能恢复。Objective To evaluate the efficacy of a bedside fiberoptic bronchoscope for ventilator-associated pneumo-nia.Methods From August 2021 to August 2023,60 patients with ventilator-associated pneumonia admitted to Ren-huai City People's Hospital were randomly selected as study objects.According to the random number table method,they were divided into two groups,30 cases in each group.The control group was treated with traditional treatment,and the observation group was treated with bedside fiberoptic bronchoscopy.The clinical efficacy,respiratory mechan-ics parameters,inflammatory factor levels and clinical symptom scores of the two groups before and after treatment were recorded and compared.Results Before treatment,there were no significant differences in quality of life,inflam-matory factor levels and clinical symptom scores between the two groups(all P>0.05).After treatment,the total clini-cal efficacy of the observation group was higher than that of the control group,and the respiratory mechanics param-eters were lower than those of the control group,the differences were statistically significant(both P<0.05).The C-reactive protein was(7.13±1.01)mg/L and interleukin-6 was(98.41±11.12)pg/mL in the observation group,which were lower than(9.75±0.05)mg/L,(110.05±11.14)pg/mL in the control group,the differences were statistically signifi-cant(t=14.191,4.050,both P<0.001).The clinical symptom score of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion The bedside fiberoptic bronchos-copy treatment is helpful to regulate the level of related inflammatory factors,improve the respiratory disorder of pa-tients,and promote their lung function recovery.

关 键 词：床旁纤维支气管镜 呼吸机相关性肺炎 炎性因子 

分 类 号：R5[医药卫生—内科学]