新生儿急性肾功能损伤相关危险因素分析  

Analysis of Risk Factors Related to Acute Kidney Injury in Newnates

作　　者：张水莲 陈阳东 危夷 ZHANG Shuilian;CHEN Yangdong;WEI Yi(Department of Pediatrics,Fuzhou First General Hospital,Fuzhou 350000,Fujian,China)

机构地区：[1]福州市第一总医院儿科,福建福州350000

出　　处：《中外医疗》2024年第20期29-32,共4页China & Foreign Medical Treatment

摘　　要：目的探讨新生儿急性肾功能损伤(Acute Kidney Injury,AKI)的相关危险因素,为预防新生儿肾功能损伤提供临床数据。方法本研究回顾性选取2020年1月—2023年1月期间福州市第一总医院收治的68例新生儿AKT患儿的临床资料为病例组,同时选择该院出生但未发生新生儿AKT的91例新生儿的临床资料作为对照组。采用单因素和多因素非条件Logistic回归分析法筛选出与新生儿AKT相关的危险因素。结果单因素分析显示,早产(27周≤胎龄<37周)、出生体质量<2500 g、新生儿窒息、妊娠期高血压、妊娠期糖尿病、败血症、新生儿呼吸窘迫综合征、低体温均为新生儿AKT的影响因素(P均<0.05)。多因素分析结果显示,母亲合并妊娠期高血压(OR=5.094)、妊娠期糖尿病(OR=9.542)、早产(OR=4.125)、新生儿窒息(OR=13.915)、败血症(OR=14.724)、新生儿呼吸窘迫综合征(OR=12.595)、低体温(OR=6.711)是新生儿AKT的独立危险因素(P均<0.05)。结论妊娠期高血压、妊娠期糖尿病、早产(27周≤胎龄<37周)、新生儿窒息、败血症、新生儿呼吸窘迫综合征、低体温均为新生儿AKT的独立危险因素。Objective To investigate the risk factors of acute kidney injury(AKI)in neonates and to provide clinical data for the prevention of AKI.Methods The clinical data 68 neonates with AKT admitted to Fuzhou First General Hospital from January 2020 to January 2023 were selected as the case group,and the clinical data of 91 neonates without AKT were randomly selected as the control group,univariate and multivariate logistic regression analysis were used to screen out the risk factors associated with neonatal AKT.Results Univariate analysis showed that preterm birth(27 weeks≤gestational age<37 weeks),birth weight<2500 g,neonatal asphyxia,gestational hypertension,gestational diabetes mellitus,sepsis,neonatal respiratory distress syndrome and hypothermia were all influential factors of AKT(all P<0.05).The results of multivariate analysis showed that,mother with gestational hypertension(OR=5.094),gestational diabetes(OR=9.542),preterm birth(OR=4.125),neonatal asphyxia(OR=13.915),septicemia(OR=14.724),neonatal respiratory distress syndrome(OR=12.595),and hypothermia(OR=6.711)were neonatal emergencies in the independent risk factors of AKT(all P<0.05).Conclusion Gestational hypertension,gestational diabetes mellitus,preterm birth(27 weeks≤gestational age<37 weeks),neonatal asphyxia,sepsis,neonatal respiratory distress syndrome,and hypothermia were all independent risk AKT in newnates.

关 键 词：新生儿 急性肾功能损伤 危险因素 

分 类 号：R4[医药卫生—临床医学]