探讨应用布地奈德联合纤维支气管镜肺泡灌洗治疗小儿难治性肺炎支原体肺炎的效果  

Exploring the Effect of Budesonide Combined with Fiberoptic Bronchoscopy Alveolar Lavage in the Treatment of Pediatric Refractory Mycoplasma Pneumoniae Pneumonia in Children

作　　者：吴倩倩 彭斌 郑庆峰 WU Qianqian;PENG Bin;ZHENG Qingfeng(Department of Pediatrics,Zhangzhou Zhengxing Hospital,Zhangzhou 363000,Fujian,China)

机构地区：[1]漳州正兴医院新生儿科,福建漳州363000

出　　处：《中外医疗》2024年第20期92-95,共4页China & Foreign Medical Treatment

摘　　要：目的探究小儿难治性肺炎支原体肺炎患儿采取布地奈德联合纤维支气管镜(简称纤支镜)肺泡灌洗治疗的临床治疗效果。方法回顾性选取2023年6月—2024年1月漳州正兴医院收治的110例小儿难治性肺炎支原体肺炎患儿的临床资料,按照不同治疗方法将患儿分为对照组(55例,单纯雾化治疗)和观察组(55例,纤支镜肺泡灌洗治疗)。比较两组患儿的临床指标、肺功能指标、并发症。结果观察组的发热持续时间为(6.03±1.69)d,咳嗽缓解时间为(7.76±1.09)d,哮鸣音消退时间为(6.76±1.18)d,住院时间为(6.37±1.09)d,均短于对照组,差异有统计学意义(t=6.734、8.188、5.321、7.721,P均<0.05)。第1秒用力呼气容积为(2.79±0.69)mL,用力肺活量为(2.97±0.78)mL,最大呼气流量为(3.86±1.03)mL,均高于对照组,差异有统计学意义(t=11.903、9.201、7.043,P均<0.05)。观察组并发症总发生率为1.82%,低于对照组,差异有统计学意义(χ^(2)=4.356,P<0.05)。结论采取布地奈德纤支镜肺泡灌洗治疗小儿难治性肺炎支原体肺炎,能够有效改善患儿症状,促进肺功能恢复,缩短治疗时间,提高临床治疗安全性。Objective To explore the clinical effect of budesonide combined with fiberoptic bronchoscopy(referred to as fiberscope)alveolar lavage in children with pediatric refractory mycoplasma pneumoniae pneumonia.Methods The clinical data of 110 children with pediatric refractory mycoplasma pneumoniae pneumonia admitted to Zhangzhou Zhengxing Hospital from June 2023 to January 2024 were retrospectively selected.According to different treatment methods,they were divided into control group(55 cases,simple atomization treatment)and observation group(55 cases,fiberoptic bronchoscopy alveolar lavage).The clinical indexes,pulmonary function indexes and complications were compared between children in two groups.Results The duration of fever in the observation group was(6.03±1.69)d,the cough relief time was(7.76±1.09)d,the wheezing sound regression time was(6.76±1.18)d,and the hospitalization time was(6.37±1.09)d,which were both shorter than those of the control group,the differences were statistically significant(t=6.734,8.188,5.321,7.721,all P<0.05).The forced expiratory volume in the first second was(2.79±0.69)mL,the forced vital capacity was(2.97±0.78)mL,and the peak expiratory flow was(3.86±1.03)mL,which were both higher than those in the control group,and the differences were statistically significant(t=11.903,9.201,7.043,all P<0.05).The total incidence of complications in the observation group was 1.82%,which was lower than that in the control group,the difference was statistically significant(χ^(2)=4.356,P<0.05).Conclusion Budesonide fiberoptic bronchoscopy alveolar lavage in the treatment of pediatric refractory mycoplasma pneumoniae pneumonia in children can effectively improve the symptoms of children,promote the recovery of lung function,shorten the treatment time and improve the safety of clinical treatment.

关 键 词：布地奈德 纤维支气管镜肺泡灌洗 小儿难治性肺炎支原体肺炎 住院时间 

分 类 号：R725[医药卫生—儿科]