羟考酮联合七氟烷对腹腔镜胃癌患者躁动及疼痛的影响分析  

Effect of Oxycodone Combined with Sevoflurane on Agitation and Pain in Patients with Laparoscopic Gastric Cancer

作　　者：张刚 ZHANG Gang(Department of Anesthesia,Shandong Yiyang Health Group Zibo Hospital,Zibo 255120,Shandong,China)

机构地区：[1]山东颐养健康集团淄博医院麻醉科,山东淄博255120

出　　处：《中外医疗》2024年第20期108-111,共4页China & Foreign Medical Treatment

摘　　要：目的分析羟考酮联合七氟烷对腹腔镜胃癌患者躁动及疼痛的影响。方法随机选取2023年1—10月山东颐养健康集团淄博医院收治的80例腹腔镜胃癌手术患者作为研究对象,按照随机数字表法分为两组,各40例。对照组应用七氟烷方案,观察组应用羟考酮联合七氟烷方案。对比两组麻醉诱导期呛咳率、术后躁动率及疼痛评分、术后恢复指标和不良反应总发生率。结果观察组呛咳率、躁动率分别为0和2.50%,低于对照组的12.50%、20.00%,差异有统计学意义(P均<0.05)。观察组术后自主呼吸恢复时间、拔管时间、麻醉苏醒时间均显著短于对照组,差异有统计学意义(P均<0.05)。观察组术后12 h的疼痛评分低于对照组,差异有统计学意义(P<0.05)。术后观察组不良反应总发生率为2.50%,低于对照组的15.00%,差异有统计学意义(χ^(2)=3.914,P=0.048)。结论对腹腔镜胃癌手术患者,实施羟考酮联合七氟烷能够减少术后躁动及不良反应发生,并且有效缓解疼痛,应用价值较高。Objective Analyze the effect of hydroxycodone combined with sevoflurane on restlessness and pain in laparoscopic gastric cancer patients.Methods From January to October 2023,80 patients with laparoscopic gastric cancer surgery admitted to Zibo Hospital of Shandong Yiyang Health Group were selected as the randomly research objects.They were divided into two groups according to the random number table method,with 40 cases in each group.The control group was treated with sevoflurane regimen,and the observation group was treated with oxycodone combined with sevoflurane regimen.The cough rate during anesthesia induction,postoperative agitation rate and pain score,postoperative recovery index and total incidence of adverse reactions were compared between the two groups.Results The cough rate and agitation rate of the observation group were 0 and 2.50%,respectively,which were lower than 12.50%and 20.00%of the control group,and the differences were statistically significant(both P<0.05).The postoperative spontaneous breathing recovery time,extubation time and anesthesia recovery time in the observation group were significantly shorter than those in the control group,and the differences were statistically significant(all P<0.05).The pain score of the observation group at 12 h after operation was lower than that of the control group,and the difference was statistically significant(P<0.05).The total incidence of adverse reactions in the observation group was 2.50%,which was lower than 15.00%in the control group,and the difference was statistically significant(χ^(2)=3.914,P=0.048).Conclusion For patients undergoing laparoscopic gastric cancer surgery,oxycodone combined with sevoflurane can reduce postoperative agitation and adverse reactions,and effectively relieve pain,with high application value.

关 键 词：羟考酮 七氟烷 腹腔镜 胃癌 躁动 疼痛 

分 类 号：R614[医药卫生—麻醉学]