肝癌自发性破裂出血患者经肝动脉化疗栓塞术后感染的影响因素分析  

Analysis on Influencing Factors of Infection After Hepatic Transarterial chemoembolization in Patients with Sponta⁃neous Rupture and Hemorrhage of Hepatocellular Carcinoma

作　　者：刘亚东 胡少辉[2] Liu Yadong;Hu Shaohui(Postgraduate Training Base of Jinzhou Medical University in The Central Hospital of Xiaogan1,Xiaogan 432000,Hubei Province,China;Hepatobiliary Spleen and Pancreatic Surgery Division,General Surgery Department,Wuhan University of Science and Technology Affiliated Xiaogan Hospital(The Central Hospital of Xiaogan)2,Xiaogan 432000,Hubei Province,China)

机构地区：[1]锦州医科大学孝感市中心医院研究生培养基地,湖北孝感432000 [2]武汉科技大学附属孝感医院(孝感市中心医院)普外肝胆脾胰外科,湖北孝感432000

出　　处：《中国社区医师》2024年第19期40-42,共3页Chinese Community Doctors

摘　　要：目的:调查肝癌自发性破裂出血患者经肝动脉化疗栓塞术(TACE)后感染情况,分析其影响因素。方法:选取2018年9月—2022年9月于孝感市中心医院行TACE的肝癌自发性破裂出血患者107例作为研究对象,根据患者术后是否出现感染分为感染组和非感染组,比较两组相关资料,分析肝癌自发性破裂出血患者TACE后感染的影响因素。结果:107例肝癌自发性破裂出血患者术后发生感染40例。合并糖尿病、存在乙型病毒性肝炎病史、发生休克、术中出血量大是肝癌自发性破裂出血患者TACE后感染的独立危险因素,清蛋白水平高是肝癌自发性破裂出血患者TACE后感染的独立保护因素(P<0.05)。结论:肝癌自发性破裂出血患者TACE后感染的独立影响因素包括合并糖尿病情况、乙型病毒性肝炎病史、清蛋白水平、休克情况、术中出血量,临床应对术后高危感染人群制定针对性防控措施。Objective:To investigate the infection after hepatic transarterial chemoembolization in patients with spontaneous rupture and hemorrhage of hepatocellular carcinoma,and analyze its influencing factors.Methods:A total of 107 patients with spontaneous rupture and hemorrhage of hepatocellular carcinoma who received hepatic transarterial chemoembolization at the Central Hospital of Xiaogan from September 2018 to September 2022 were selected as the study subjects.According to the presence of postoperative infection,the patients were divided into infection group and non-infection group.The relevant data of the two groups were compared.The influencing factors of infection after hepatic transarterial chemoembolization in patients with spontaneous rupture and hemorrhage of hepatocellular carcinoma were analyzed.Results:Among the 107 patients with spontaneous rupture and hemorrhage of hepatocellular carcinoma,40 cases developed postoperative infection.The complicated diabetes mellitus,presence of viral hepatitis B history,occurrence of shock,and high intraoperative blood loss were independent risk factors for infection after hepatic transarterial chemoembolization in patients with spontaneous rupture and hemorrhage of hepatocellular carcinoma,and high level of serum albumin was an independent protective factor for infection after hepatic transarterial chemoembolization in patients with spontaneous rupture and hemorrhage of hepatocellular carcinoma(P<0.05).Conclusion:The independent influencing factors of infection after hepatic transarterial chemoembolization in patients with spontaneous rupture and hemorrhage of hepatocellular carcinoma include the complicated diabetes mellitus,history of viral hepatitis B,serum albumin level,shock,and intraoperative blood loss.In clinical setting,targeted prevention measures should be formulated for population at high risk postoperative infection.

关 键 词：肝癌自发性破裂出血 经肝动脉化疗栓塞术 感染 

分 类 号：R473.73[医药卫生—护理学]