亲水改性UiO-66修饰电极的抗污染性能  

Antifouling Property of Hydrophilic UiO-66 Modified Electrodes

作　　者：刘耘希 赵凡 LIU Yunxi;ZHAO Fan(Tianjin Key Laboratory of Structure and Performance for Functional Molecules,College of Chemistry,Tianjin Normal University,Tianjin 300387,China)

机构地区：[1]天津师范大学化学学院,天津师范大学天津市功能分子结构与性能重点实验室,天津300387

出　　处：《广州化学》2024年第4期55-58,I0003,共5页Guangzhou Chemistry

基　　金：天津市大学生创新创业训练计划项目(202210065164)。

摘　　要：合成了亲水性不同的金属有机框架化合物UiO-66、UiO-66-NH_(2)和UiO-66-(OH)_(2),再用滴涂法制备了三种修饰电极UiO-66/GCE、UiO-66-NH_(2)/GCE和UiO-66-(OH)_(2)/GCE,采用差分脉冲伏安法比较了三种电极的抗污能力。结果表明,与传统的UiO-66相比,UiO-66-NH_(2)表现出更强的抗蛋白质非特异性吸附能力,峰电流信号的保留程度高达95%,这归功于UiO-66-NH_(2)良好的亲水性,有利于在电极表面形成水化层,产生物理及能量势垒,阻止了蛋白质等疏水物质靠近电极表面。UiO-66-NH_(2)修饰电极还表现出良好的稳定性,经过长时间测试后,电流保留值高达91%。因此,UiO-66有望作为一类新的电极抗污材料应用于电化学生物传感器的构建,为复杂环境中物质的准确分析提供了一种新的策略。The antifouling property of hydrophilic UiO-66(UiO-66,UiO-66-NH_(2) and UiO-66-(OH)_(2))modified electrodes was investigated.The peak current obtained from UiO-66-NH_(2)/GCE modified electrode retained up to 95%of the original value in FcMeOH solution.This phenomenon was attributed to the excellent hydrophilicity of UiO-66-NH_(2) that facilitated the formation of a hydration layer on the electrode surface,which created a physical and energetic barrier that prevented hydrophobic substances,such as proteins,from approaching the electrode surface.In addition,UiO-66-NH_(2)/GCE modified electrode also exhibited long-term stability.Therefore,UiO-66 can be utilized as a new class of antifouling materials.This study also provided an effective strategy for the construction of electrochemical biosensors with good antifouling ability and stability.

关 键 词：纳米材料 金属有机框架化合物 UiO-66 电极抗污染 电化学生物传感器 

分 类 号：O657[理学—分析化学]