用于小口径5 T磁共振成像系统的梯度线圈和^(1)H/^(13)C双共振射频线圈研制  

Development of Gradient Coils and^(1)H/^(13)C Dual-resonance RF Coils for a Small-bore 5 T MRI System

作　　者：易鹏 曹丽 黄臻 程鑫 王佳鑫 陈黎 陈方 鲍庆嘉 张志 刘朝阳 YI Peng;CAO Li;HUANG Zhen;CHENG Xin;WANG Jiaxin;CHEN Li;CHEN Fang;BAO Qingjia;ZHANG Zhi;LIU Chaoyang(School of Electrical and Electronic Engineering,Wuhan Polytechnic University,Wuhan 430023,China;State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics,National Center for Magnetic Resonance in Wuhan(Innovation Academy for Precision Measurement Science and Technology,Chinese Academy of Sciences),Wuhan 430071,China;University of Chinese Academy of Sciences,Beijing 100049,China)

机构地区：[1]武汉轻工大学电气与电子工程学院,湖北武汉430023 [2]波谱与原子分子物理国家重点实验室,武汉磁共振中心(中国科学院精密测量科学与技术创新研究院),湖北武汉430071 [3]中国科学院大学,北京100049

出　　处：《波谱学杂志》2024年第3期245-256,共12页Chinese Journal of Magnetic Resonance

基　　金：国家重点研发计划项目(2023YFE0113300,2022YFF0707000);中国科学院磁共振技术联盟科研仪器设备研制项目(2021-GZL001);中国科学院基础与交叉前沿科研先导专项(XDB0540300);国家自然科学基金项目(22327901,81627901,22374158,22127801,21927801,12205352,22204168);中国科学院精密测量科学与技术创新研究院交叉培育项目(S21S4101);中国科学院科研仪器研制项目(YJKYYQ20190032)。

摘　　要：基于自主研制的5 T磁共振成像系统和^(13)C代谢磁共振成像研究需求,设计了一种小口径磁共振成像梯度线圈和^(1)H/^(13)C双共振射频线圈系统.其中梯度线圈设计采用有限差分流函数方法,射频线圈设计为马鞍线圈结合表面线圈的双共振方案.采用有限元方法对磁场分布进行了数值模拟分析,成功研制出一套用于小口径5 T^(13)C磁共振成像的梯度与射频线圈,并利用自主研制的5 T磁共振成像系统平台验证了设计方案的可行性,经过实验测试采集到^(13)C标记的尿素水模磁共振图像和小鼠头部^(1)H磁共振图像,为后续开展基于动态核极化的^(13)C磁共振代谢成像奠定了基础.Based on the independently developed 5 T magnetic resonance imaging(MRI)system and research needs of^(13)C metabolic MRI,a gradient coil and^(1)H/^(13)C dual resonance radiofrequency(RF)coil system for small-bore MRI were designed.The gradient coil was designed by using the finite-difference stream function method,and the RF coil was designed as a saddle coil combined with a surface coil in a dual-resonance scheme.Numerical simulation analysis of the magnetic field distribution was carried out by using the finite-element method,and a set of gradient and RF coils for small-bore 5 T^(13)C MRI was successfully developed.The feasibility of the design scheme was verified using a home-made 5 T MRI system,and the magnetic resonance images of^(13)C-labeled urea phantom and^(1)H magnetic resonance images of mice head were acquired by experimental tests,which lays a foundation for^(13)C metabolic MRI based on dynamic nuclear polarization in the future.

关 键 词：高场磁共振成像 ^(13)C代谢磁共振成像 梯度线圈 ^(1)H/^(13)C双共振线圈 马鞍线圈 表面线圈 

分 类 号：O482.53[理学—固体物理]