枯草芽胞杆菌对大肠杆菌返饲母猪繁殖性能和健康度的影响  

Effects of Bacillus subtilis on reproductive performance and health of gestating sows after back-feeding with Escherichia coli

作　　者：刘建新 葛雷 屈浩博 黄克和[1] LIU Jianxin;GE Lei;QU Haobo;HUANG Kehe(Institute of Animal Nutritional Health,Nanjing Agricultural University,Nanjing 210095,China;Jiangsu Academy of Agricultural Sciences,Nanjing 210095,China)

机构地区：[1]南京农业大学动物营养健康研究所,江苏南京210095 [2]江苏省农业科学院,江苏南京210095

出　　处：《畜牧与兽医》2024年第9期56-60,共5页Animal Husbandry & Veterinary Medicine

基　　金：国家自然科学基金联合基金重点项目(U22A20524)。

摘　　要：旨在探究枯草芽胞杆菌对围产期母猪返饲大肠杆菌病料后繁殖性能和健康度的影响。选取20头预产期相近的大白母猪随机分为对照组和试验组,每组10头;在母猪产前第35天,对试验组母猪每头每日添加5 g枯草芽胞杆菌(2×10^(8)CFU/g)至断奶;在产前第21天,对两组母猪均进行大肠杆菌病料返饲;在产前1 d,每组随机采集5头母猪的耳缘静脉血用于检测免疫指标和抗氧化指标,记录母猪繁殖性能指标、子代生长性能指标和母猪围产期粪便指数、乳房健康指数及子宫内膜炎指数。结果:与对照组相比,添加枯草芽胞杆菌可以显著降低大肠杆菌返饲母猪的死胎数,提升活产数(P<0.05),显著降低母猪产前氧化应激和炎症水平及产前便秘、产后乳房炎和产后子宫内膜炎发生率(P<0.05),显著增加其子代断奶窝重和断奶时存活率(P<0.05)。综上,枯草芽胞杆菌可以有效提升大肠杆菌返饲母猪繁殖性能和围产期健康度,并降低其子代在哺乳期间的死亡率,为防控哺乳仔猪大肠杆菌性腹泻提供了新思路。This study was to investigate the effects of Bacillus subtilis on reproductive performance and health status of gestating sow backfed with Escherichia coli in the feed.Twenty Large White sows with similar farrowing dates were obtained and randomly divided into two groups with 10 sows in each group,which were the control group and the experimental group,respectively.On the 35th day before delivery,each sow in the experimental group was fed with a diet added with 5 g Bacillus subtilis daily until weaning.On the 21st day before delivery,the sows in both groups were back-fed with Escherichia coli in the diet.One day before delivery,the ear edge venous blood samples of 5 sows in each group were randomly collected for the detection of immune indexes and antioxidant indexes.Then,the reproduction performance,piglet growth performance data,mammary gland health index,endometritis index and fecal index of the sows during lactation were recorded.The results showed that,compared with the control group,the addition of Bacillus subtilis effectively reduced the number of stillbirths and increased the number of live births of the sows fed with Escherichia coli in the diet(P<0.05),weakened the levels of oxidative stress and inflammation in the prenatal sows,lowered the incidence of postpartum mastitis and postpartum endometritis(P<0.05)in them,and raised the weaning litter weight and weaning survival rate of the offspring(P<0.05).In conclusion,Bacillus subtilis effectively improved the reproductive performance and perinatal health of sows back-fed with Escherichia coli in their diet,and reduced the mortality of their offspring during breastfeeding,which might be a new idea for the prevention and control of Escherichia coli diarrhea of suckling piglets.

关 键 词：枯草芽胞杆菌 大肠杆菌返饲 繁殖性能 氧化应激 炎症 

分 类 号：S852.6[农业科学—基础兽医学]