Acute Effects of Exposure to Fine Particulate Matter and Its Constituents on Sex Hormone Among Postmenopausal Women — Beijing, Tianjin, and Hebei PLADs, China, 2018–2019  

作　　者：Yanlin Tian Jiaonan Wang Jianlong Fang Chen Chen Feng Zhao Yi Zhang Peng Du Yawei Li Wanying Shi Yuanyuan Liu Enmin Ding Song Tang Xu Yue Xiaoming Shi 

机构地区：[1]Chinese Research Academy of Environmental Sciences,Beijing,China [2]Collaborative Innovation Center of Atmospheric Environment and Equipment Technology,Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control(AEMPC),Nanjing University of Information Science&Technology,Nanjing City,Jiangsu Province,China [3]China CDC Key Laboratory of Environment and Population Health,National Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing,China [4]Department of Epidemiology and Health Statistics,School of Public Health,Capital Medical University,and Beijing Municipal Key Laboratory of Clinical Epidemiology,Beijing,China [5]National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases,National Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing,China

出　　处：《China CDC weekly》2024年第13期249-253,I0001-I0004,共9页中国疾病预防控制中心周报（英文）

基　　金：Supported by the National Natural Science Foundation of China(No.82025030,No.81941023);the National Key Research and Development Program of China(No.2022YFC3702700);the Open Fund provided by the Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control(KHK 2104).

摘　　要：What is already known on this topic?Exposure to fine particulate matter(PM_(2.5))was linked to endocrine hormone disruption in the reproductive system.Nonetheless,it was unclear which specific components of PM_(2.5) were primarily responsible for these associations.What is added by this report?The study presented the initial epidemiological evidence that brief exposure to PM_(2.5) can elevate estradiol levels in postmenopausal women.Various particle components had unique effects,with watersoluble ions and specific inorganic elements like Ag,As,Cd,Hg,Ni,Sb,Se,Sn,and Tl potentially playing significant roles in increasing estradiol levels.What are the implications for public health practice?The study established that the prevalence of air pollution,along with its specific components,has been recognized as a novel risk factor affecting the balance of sex hormones.

关 键 词：POLLUTION PARTICULATE primarily 

分 类 号：R71[医药卫生—妇产科学]