海南省2008—2023年登革热流行病学特征  

Epidemiological characteristics of dengue fever in Hainan Province from 2008 to 2023

作　　者：陈菁菁[1,2] 孟纬纬 贾鹏本 邱丽[1,2] 张玲 罗艳[1,2] 谢永慧 金玉明 CHEN Jingjing;MENG Weiwei;JIA Pengben;QIU Li;ZHANG Ling;LUO Yan;XIE Yonghui;JIN Yuming(Hainan Center for Disease Control&Prevention,Haikou,Hainan 571129,China;Hainan Academy of Preventive Medicine,Haikou,Hainan 571129,China;School of Public Health,Hainan Medical University,Haikou,Hainan 571199,China)

机构地区：[1]海南省疾病预防控制中心,海南海口571129 [2]海南省预防医学科学院,海南海口571129 [3]海南医科大学公共卫生学院,海南海口571199

出　　处：《中国热带医学》2024年第8期936-941,共6页China Tropical Medicine

基　　金：海南省自然科学基金项目(No.820MS158)。

摘　　要：目的通过分析海南省2008—2023年报告登革热病例的流行病学特征及影响因素,为完善登革热的防控策略和措施提供科学依据。方法采用描述性流行病学方法分析2008—2023年海南省报告登革热病例的时间、空间和人群分布特征及其影响因素,同时选用Spearman相关性分析探究本地病例和输入性病例的相关性,运用ArcGIS 10.8和R 4.3.0进行图形的制作,并采用SaTScan 10.1.3软件进行时空扫描分析。结果海南省2008—2023年共报告登革热病例810例,其中输入性病例164例,本地病例646例。2008—2023年646例本地病例报告于6—12月,具有明显的季节性特征,9—10月为高发月份,主要分布于海口市(41.18%)和乐东黎族自治县(39.32%);2019和2023年发生了2次登革热较大规模暴发,本地病例数分别达到302和328例(共占本地病例总数97.52%);本地病例的男女性别比为1.57∶1;25~<65岁年龄组的病例占69.50%;本地病例数居前3位的职业是家务及待业(17.65%)、民工(17.34%)和商业服务(13.78%)。2008—2023年共报告164例输入性病例,各月份均有报告,高发月份为6—11月,占输入性病例总数的82.32%。共报告境内输入病例66例,来源于广东省、云南省和广西壮族自治区;境外输入98例,主要来源于泰国和柬埔寨;输入性病例数男女性别比为1.65∶1;25~<55岁年龄组的病例占68.29%;输入性病例数居前3位的职业是商业服务(33.54%)、家务及待业(10.37%)和农民(9.76%)。2008—2013年期间海南省报告境内输入性病例年份为2014年、2018年、2019年和2023年,与2008—2013年海南省本地病例报告年份基本相同,且本地病例与境内输入性病例之间存在正相关关系(r=0.892,P<0.001),与境外输入性病例相关性无统计学意义。时空扫描分析结果共探测出5个聚集区,聚集时间集中在2019年和2023年的9—10月。结论海南省登革热疫情多发,主要由输入性病例引起本地暴发,未形成地方性Objective To provide a scientific basis for improving the prevention and control strategies of dengue fever by analyzing the epidemiological characteristics and influencing factors of reported cases in Hainan Province from 2008 to 2023.Methods Descriptive epidemiological methods were used to analyze the temporal,spatial,and demographic distribution characteristics and influencing factors of reported dengue fever cases in Hainan Province from 2008 to 2023.Spearman correlation analysis was used to explore the correlation between local cases and imported cases.ArcGIS 10.8 and R 4.3.0 were used for graphic production,and SaTScan 10.1.3 software was used for spatiotemporal scanning analysis.Results From 2008 to 2023,a total of 810 cases of dengue fever were reported in Hainan Province,including 164 imported cases and 646 local cases.The 646 local cases reported from June to December,showed a significant seasonal pattern,with September to October being the peak months.The cases were mainly distributed in Haikou City(41.18%)and Ledong County(39.32%).There were two large-scale outbreaks of dengue fever in 2019 and 2023,with 302 and 328 local cases reported respectively(accounting for 97.52%of the total local cases).The male-to-female ratio of local cases was 1.57:1,and cases in the age group of 25 to under 65 accounted for 69.50%of the total.The top three occupations of local cases were housework and unemployment(17.65%),migrant workers(17.34%),and business services(13.78%).From 2008 to 2023,a total of 164 imported cases were reported,with cases reported every month.The peak months were from June to November,accounting for 82.32%of the total imported cases.A total of 66 domestically imported cases were reported,originating from Guangdong Province,Yunnan Province,and Guangxi Zhuang Autonomous Region;98 cases were overseas imports,mainly from Thailand and Cambodia.The male-to-female ratio of imported cases was 1.65:1,and cases in the age group of 25 to under 55 accounted for 68.29%of the total.The top three occupations of

关 键 词：登革热 流行病学特征 时空扫描 海南省 

分 类 号：R181.3[医药卫生—流行病学] R512.8[医药卫生—公共卫生与预防医学]