2023年重庆市高中学生结核分枝杆菌潜伏感染现状及影响因素分析  

Analysis of status and influencing factors of latent tuberculosis in fection among high school students,Chongqing,2023

作　　者：钱金山 余雅 吴成果 石亚玲 刘英 尹进 苏倩 黄学勇 王梅 曾庆[1] 吴波 QIAN Jin-shan;YU Ya;WU Cheng-guo;SHI Ya-ling;LIU Ying;YIN Jin;SU Qian;HUANG Xue-yong;WANG Mei;ZENG Qing;WU Bo(College of Public Health,Chongqing Medical University,Chongqing 401331,China;不详)

机构地区：[1]重庆医科大学公共卫生学院,重庆401331 [2]重庆市结核病防治所

出　　处：《现代预防医学》2024年第16期2960-2965,3009,共7页Modern Preventive Medicine

基　　金：重庆市科卫联合医学科研重点项目(基金号2023ZDXM 027);重庆市科卫联合医学科研面上项目(基金号2023MS XM143);重庆市公共卫生重点专科(学科)建设经费资助。

摘　　要：目的探索重庆市高中学生结核分枝杆菌潜伏感染现状及影响因素,为重庆市学校结核病防控提供参考。方法采用分层整群抽样方法,抽取2023年重庆市高一、高二年级学生为研究对象,用重组结核分枝杆菌融合蛋白皮肤试验检测结核分枝杆菌潜伏感染情况,收集结核分枝杆菌潜伏感染的相关信息,采用logistic回归模型分析影响因素。结果共纳入重庆市高一、高二年级学生9161人,检出结核分枝杆菌潜伏感染543人,结核分枝杆菌潜伏感染率为5.93%。多因素logistic回归分析显示,既往结核病史(OR:4.244,95%CI:2.239~8.044)、结核病密切接触史(OR:2.096,95%CI:1.123~3.914)、吸烟(OR:6.819,95%CI:3.562~13.053)、熬夜(OR:1.665,95%CI:1.154~2.402)是学生结核分枝杆菌潜伏感染的危险因素。结论重庆市高一、高二年级学生结核分枝杆菌潜伏感染率较低。做好个人防护措施,加强身体锻炼,提高自身免疫力,可降低学生感染结核分枝杆菌的风险。Objective To explore the status and influencing factors of latent tuberculosis infection among high school students in Chongqing,and to provide technical support for the prevention and control of tuberculosis in schools in Chongqing.Methods Stratified cluster sampling method was used to select the students of the first and second years of high school in Chongqing in 2023,as the study subjects to detect latent tuberculosis infection with recombinant Mycobacterium tuberculosis fusion protein skin test,to collect the information related to latent tuberculosis infection,and to analyse the influencing factors using Logistic regression model.Results A total of 9161 students in the first and second years of high school in Chongqing were included,and 543 latent tuberculosis infections were detected,with a latent tuberculosis infection rate of 5.93%.Multifactorial logistic regression analysis showed that history of previous tuberculosis(0R:4.244,95%CI:2.239-8.044),history of close contact with tuberculosis(OR:2.096,95%CI:1.123-3.914),smoking(OR:6.819,95%CI:3.562-13.053),and staying up late(OR:1.665,95%CI:1.154-2.402)were risk factors for latent tuberculosis infection in students.Conclusion The rate of latent tuberculosis infection among students in the first and second years of high school in Chongqing is low.Not smoking,not staying up late,avoiding close contact with tuberculosis patients,taking good personal protective measures,strengthening physical exercise,and improving immunity can reduce the risk of students being infected with Mycobacterium tuberculosis.

关 键 词：结核病 学生 结核分枝杆菌潜伏感染 影响因素 皮肤试验 

分 类 号：R521[医药卫生—内科学]