贵阳市男男性行为者HIV暴露前预防使用意愿及其相关因素研究  

Willingness to use HIV pre-exposure prophylaxis and related factors of men who have sex with men,Guiyang City

作　　者：佘敏[1] 马璐[1] 李劲[1] 袁乡石 祝继[1] 张欐 杨琴[1] 黄斌[1] 包愿 徐素芹 申万敏 SHE Min;MA Lu;LI Jin;YUAN Xiang-shi;ZHU Ji;ZHANG Li;YANG Qin;HUANG Bin;BAO Yuan;XU Su-qin;SHEN Wan-min(Guiyang Center for Disease Control and Prevention,Guiyang,Guizhou 550018,China;不详)

机构地区：[1]贵阳市疾病预防控制中心,贵州贵阳550018 [2]贵州医科大学公共卫生与健康学院

出　　处：《现代预防医学》2024年第16期3035-3041,3072,共8页Modern Preventive Medicine

基　　金：贵州省卫生健康委科学技术基金项目(gzwkj2023-480)。

摘　　要：目的了解贵阳市男男性行为者(Men who have sex wih men,MSM)HIV暴露前预防(PrEP)使用意愿,探索相关因素,为贵阳市及贵州省推广PrEP工作提供参考依据。方法2022年4—6月,通过贵阳市两家社会组织,采用方便抽样的方法在MSM酒吧、微信群等社交场所及互联网招募调查对象,问卷使用“问卷星”平台收集。调查内容主要包括人口学信息、行为学特征、PrEP知识知晓及使用意愿等情况,PrEP使用意愿的单因素分析运用卡方检验,二分类logistic回归模型进行PrEP使用意愿的多因素分析。结果收集有效问卷608份,共有146人(24.0%)知晓PrEP,216人(35.5%)既往使用过PrEP,如果发生感染艾滋病的高危行为,525人(86.3%)愿意采用暴露前预防。多因素分析结果显示,非贵阳市户籍(OR=3.09,95%CI:1.42~6.73)、在贵阳市居住7~12个月(OR=5.12,95%CI:2.25~11.65)和12个月以上(OR=4.19,95%CI:1.85~9.49),在职(OR=17.05,95%CI:4.14~70.26)、待业或无业(OR=6.29,95%CI:1.18~33.59),最近1年检测过HIV(OR=3.77,95%CI:1.70~8.38),既往使用过PrEP(OR=15.85,95%CI:5.12~49.11)和知晓PrEP(OR=4.82,95%CI:1.88~12.38)的调查对象使用PrEP的愿意较高。结论贵阳市接受调查的MSM人群PrEP知晓率较低,PrEP使用意愿较高,影响因素较多,应针对影响因素,制定针对性的PrEP用药知识宣传措施,进一步提高MSM人群的PrEP知识知晓、对使用PrEP效果的信心和使用意愿,在使用安全套等艾滋病综合防治的前提下推广使用PrEP,降低感染HIV的风险。Objective To understand the willingness to use pre-exposure prophylaxis(PrEP)among MSM in Guiyang,explore related factors,so as to provide reference for promoting PrEP in Guiyang and Guizhou Province.Methods Two social organizations in Guiyang were recruited among MSM from gay bars,WeChat groups and other social venues and the Internet by convenient sampling method from April to June,2022.Questionnaires were collected using the“Wen Juan Xing”platform,the contents of the survey included demographic information,behavioral characteristics,knowledge of PrEP,the willingness to use PrEP and so on.Univariate analysis of the willingness to use PrEP was used Chi-square test,logistics regression was carried out to analyze the multiple-factors related to the willingness to use PrEP.Taking the willingness to use PrEP as the dependent variable,univariate and multivariate logistics regression was carried out to analyze the factors related to the willingness to use PrEP.Results 608 valid questionnaires were collected.A total of 146 people(24.0%)knew about PrEP,216 people(35.5%)had used PrEP before,and 525 people(86.3%)were willing to use PrEP if they had high-risk behaviors.The results of multivariate analysis showed that non-Guiyang resident(OR=3.09,95%CI:1.42-6.73),living in Guiyang for 7-12 months(OR=5.12,95%CI:2.25-11.65)and more than 1 year(OR=4.19,95%CI:1.85-9.49),employed(OR=17.05,95%CI:4.14-70.26),unemployed(OR=6.29,95%CI:1.18-33.59),tested for HIV in the last 1 year(OR=3.77,95%CI:1.70-8.38),those who had previously used PrEP(OR=15.85,95%CI:5.12-49.11)and aware of PrEP(OR=4.82,95%CI:1.88-12.38)were more likely to use PrEP.Conclusion The MSM population surveyed in Guiyang has a low awareness rate of PrEP,higher willingness to use PrEP,and relative factors,develop targeted measures to promote knowledge about PrEP according to relative factors,so as to improve the knowledge of PrEP,confidence and willingness to use PrEP.Promote the use of PrEP in the context of comprehensive AIDS prevention and control,such as the use

关 键 词：男男性行为者 知晓 暴露前预防 使用意愿 相关因素 

分 类 号：R512.91[医药卫生—内科学]