融合多感官刺激的虚拟现实—脑机接口手功能增强康复系统  

Virtual reality-brain computer interface hand function enhancement rehabilitation system incorporating multi-sensory stimulation

作　　者：邵谢宁 张艺滢 张栋 门延帝 王子龙 陈晓玲[1,2] 谢平 SHAO Xiening;ZHANG Yiying;ZHANG Dong;MEN Yandi;WANG Zilong;CHEN Xiaoling;XIE Ping(College of Electrical Engineering,Yanshan University,Qinhuangdao,Hebei 066000,P.R.China;Key Lab of Intelligent Rehabilitation and Neuromodulation of Hebei Province,Qinhuangdao,Hebei 066000,P.R.China;School of Design and Art,Beijing Institute of Technology,Beijing 100081,P.R.China)

机构地区：[1]燕山大学电气工程学院,河北秦皇岛066000 [2]河北省智能康复及神经调控重点实验室,河北秦皇岛066000 [3]北京理工大学设计与艺术学院,北京100081

出　　处：《生物医学工程学杂志》2024年第4期656-663,共8页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(U20A20192);河北省自然科学基金资助项目(F2022203079);河北省创新能力提升计划项目(22567619H)。

摘　　要：脑卒中(stroke)是由于脑部血液供应突然中断或脑血管破裂,导致脑细胞损伤进而损害患者运动和认知能力的一种急性脑血管疾病。融合脑—机接口(BCI)和虚拟现实(VR)的新型康复训练模式,不仅能促进脑网络功能激活,而且能为患者提供沉浸感强、趣味性强的情境反馈。本文设计了融合多感官刺激反馈、BCI和VR的手部康复训练系统,通过虚拟场景的任务引导患者运动想象,获取患者运动意图,进而在虚拟场景下进行人机交互;同时,融入触觉反馈进一步增加患者本体感受,从而实现基于视、听、触觉多感官刺激反馈的手功能康复训练。本研究通过对比分析加入触觉反馈前后的脑电信号数据内不同频段功率谱密度的差异,发现加入触觉反馈后运动脑区被明显激活,运动脑区的功率谱密度在高γ频段有显著提升。研究结果说明,患者在融合多感官刺激的VR—BCI手功能增强康复系统中进行康复训练,能够加速感觉传导通路和运动传导通路的双向促通,从而加速康复进程。Stroke is an acute cerebrovascular disease in which sudden interruption of blood supply to the brain or rupture of cerebral blood vessels cause damage to brain cells and consequently impair the patient's motor and cognitive abilities.A novel rehabilitation training model integrating brain-computer interface(BCI)and virtual reality(VR)not only promotes the functional activation of brain networks,but also provides immersive and interesting contextual feedback for patients.In this paper,we designed a hand rehabilitation training system integrating multi-sensory stimulation feedback,BCI and VR,which guides patients'motor imaginations through the tasks of the virtual scene,acquires patients'motor intentions,and then carries out human-computer interactions under the virtual scene.At the same time,haptic feedback is incorporated to further increase the patients'proprioceptive sensations,so as to realize the hand function rehabilitation training based on the multi-sensory stimulation feedback of vision,hearing,and haptic senses.In this study,we compared and analyzed the differences in power spectral density of different frequency bands within the EEG signal data before and after the incorporation of haptic feedback,and found that the motor brain area was significantly activated after the incorporation of haptic feedback,and the power spectral density of the motor brain area was significantly increased in the high gamma frequency band.The results of this study indicate that the rehabilitation training of patients with the VR-BCI hand function enhancement rehabilitation system incorporating multi-sensory stimulation can accelerate the two-way facilitation of sensory and motor conduction pathways,thus accelerating the rehabilitation process.

关 键 词：脑—机接口 虚拟现实 触觉反馈 手功能康复 多感官刺激反馈 

分 类 号：TN911.7[电子电信—通信与信息系统] R496[电子电信—信息与通信工程]