李斯特菌感染对人和反刍动物母体妊娠影响的研究进展  

Progress in understanding of the effects of Listeria monocytogenes infection on maternal pregnancy in humans and ruminants

作　　者：李康莉 刘犇 周伟华[1] LI Kang-li;LIU Ben;ZHOU Wei-hua(Yichun University,Yichun 336000,China;Jiangxi Lvke Agriculture and Animal Husbandry Technology Co.LTD.,Yichun 336000,China)

机构地区：[1]宜春学院,宜春336000 [2]江西绿科农牧科技有限公司,宜春336000

出　　处：《中国人兽共患病学报》2024年第7期656-661,共6页Chinese Journal of Zoonoses

基　　金：江西省教育厅科技项目(No.GJJ211630,No.GJJ201622);江西现代农业科研协同创新专项(No.JXXTCX201702)。

摘　　要：单核细胞增生李斯特菌(Listeria monocytogenes,LM)是一种兼性胞内寄生的革兰氏阳性短杆菌,可引起人及动物李斯特菌病,是全球四大食源性致病菌之一。由于妊娠相关免疫缺陷及LM对生殖器官的趋向性,导致孕期易感。妊娠合并LM感染与妊娠期流产、早产和新生儿并发症密切相关。本文介绍国内外妊娠合并LM感染的相关事件,详细讨论李斯特菌病诊断、治疗的最新进展,并着重分析妊娠合并LM感染的产科结局,以期为今后防控人类及反刍动物妊娠期LM感染及食品安全提供参考。Listeria monocytogenes(LM)is a parthenogenetic intracellular parasitic Gram-positive short bacillus that causes listeriosis in humans and animals.LM is considered one of the four major food pathogens in the world.Infection susceptibility during pregnancy is due to pregnancy-associated immunodeficiency and LM’s tropism toward reproductive organs.LM infection in pregnancy is strongly associated with miscarriage,preterm labor,and neonatal complications.This article describes events related to LM infection in pregnancy in China and other countries;discusses recent advances in the diagnosis and treatment of listeriosis in detail;and focuses on the obstetric outcomes of LM infection in pregnancy.The aim of this article is to provide a reference for the future prevention and control of LM infection in pregnancy in humans and ruminants,as well as to support food safety.

关 键 词：单核细胞增生李斯特菌 妊娠期 流产 新生儿 

分 类 号：R378.99[医药卫生—病原生物学]