2μm激光消融技术在生物组织中的应用  

Application of 2μm laser ablation technology in biological tissues

作　　者：张誉 张雯[1,2] ZHANG Yu;ZHANG Wen(Key Laboratory of the Ministry of Education for Optoelectronic Measurement Technology and Instrument,Beijing Information Science&Technology University,Beijing 100192,China;Beijing Laboratory of Fiber Optic Sensing and Systems,Beijing Information Science&Technology University,Beijing 100016,China)

机构地区：[1]北京信息科技大学光电测试技术及仪器教育部重点实验室,北京100192 [2]北京信息科技大学光纤传感与系统北京实验室,北京100016

出　　处：《北京信息科技大学学报（自然科学版）》2024年第4期1-12,共12页Journal of Beijing Information Science and Technology University

基　　金：国家自然科学基金项目(52275517);高等学校学科创新引智计划(D17021);北京市属高校教师队伍建设支持计划(BPHR202203226)。

摘　　要：激光因其能量集中、稳定性好、易于使用等优点,越来越多地被应用于生物医疗领域。近年来,2μm激光凭借着高水分子吸收系数的优势成为生物组织消融和碎石手术的理想选择,具有极大的应用前景。简要阐述了激光消融生物组织的光分布与光传热机制,介绍了2μm激光在体外组织、体内组织和碎石手术中的应用,总结了激光功率、工作模式、脉冲频率等对不同生物组织目标的影响,得出掺铥光纤激光器具有在激光消融领域替代掺钬钇铝石榴石(Ho:YAG)激光器潜力的结论。最后,讨论了掺铥光纤激光器在生物医疗领域发展的主要问题和趋势。Due to its advantages such as energy concentration,good stability,and ease of use,lasers are increasingly used in the field of biomedicine.In recent years,the 2μm laser has become the ideal choice for biological tissue ablation and lithotripsy surgery with the advantage of high water molecular absorption coefficient,exhibiting great application prospects.The light distribution and light heat transfer mechanism of laser ablation biological tissue were briefly described,and the application of 2μm laser in vitro tissue,internal tissue and lithotripsy surgery was introduced.The effect of laser power,working mode,pulse frequency,etc on different biological tissue targets was summarized.The conclusion is that thulium-doped fiber laser(TFL)has the potential to replace Ho:YAG laser in the field of laser ablation.Finally,the main issues and trends in the development of TFL in the biomedical field were proposed.

关 键 词：激光消融 激光碎石 2ΜM激光 掺铥光纤激光器 

分 类 号：TH773[机械工程—仪器科学与技术]