合并单纯性肾囊肿的急性A型主动脉夹层患者的临床预后特点  

Clinical Prognosis in Patients with Acute Type A Aortic Dissection and Simple Renal Cyst

作　　者：付彪 王成虎 王秋吉 吴进林 李伯海[2] 范瑞新[1] FU Biao;WANG Chenghu;WANG Qiuji;WU Jinlin;LI Bohai;FAN Ruixin(Guangdong Cardiovascular Institute,Guangdong Provincial People′s Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,Guangzhou 510100,China;Guangdong Second Provincial General Hospital,Guangzhou 510317,China)

机构地区：[1]广东省心血管病研究所南方医科大学附属广东省人民医院(广东省医学科学院),广州510100 [2]广东省第二人民医院,广州510317

出　　处：《岭南心血管病杂志》2024年第4期345-350,共6页South China Journal of Cardiovascular Diseases

摘　　要：目的探讨合并单纯性肾囊肿(simple renal cyst,SRC)的急性A型主动脉夹层(acute type A aortic dissection,ATAAD)患者的临床预后特点。方法回顾性分析广东省人民医院2017年6月至2023年6月因ATAAD入院手术患者的病历资料,根据术前主动脉计算机断层扫描血管造影(computed tomography angiography,CTA)检查是否合并有SRC,将患者分为SRC组和无SRC组,将基线资料进行1∶1倾向性评分匹配校准后,比较两组患者围术期相关指标及随访的差异。结果共533例患者纳入研究,两组各有165例进入匹配队列,两组患者在神经系统、循环系统、呼吸系统、泌尿系统、消化系统及其他并发症方面比较,均差异无统计学意义(P>0.05)。术后随访发现,SRC组患者较无SRC组更易发生主动脉事件(P<0.001)。多因素COX回归分析SRC组患者较无SRC组发生主动脉终点事件的风险比为2.545(95%CI:1.668~3.883,P<0.001)。结论SRC的存在不影响多个系统并发症的发生,但是SRC的存在能提高ATAAD患者术后残存主动脉发生主动脉事件的风险。Objectives To investigate the clinical characteristics in patients with acute type A aortic dissection(ATAAD)complicated with simple renal cyst(SRC).Methods The clinical characteristic of patients with ATAAD admitted to Guangdong Provincial People′s Hospital from June 2017 to June 2023 were retrospectively analyzed.According to whether the preoperative aortic computed tomography angiography(CTA)examination was complicated with SRC,the patients were divided into SRC group and no SRC group.After 1∶1 propensity score matching calibration of the baseline,the differences in perioperative related indicators and follow-up of the two groups were compared.Results A total of 533 patients were included in the study,and 165 cases in each group were included in the matching cohort.There were no statistically significant differences in the nervous system,circulatory system,respiratory system,urinary system,digestive system and other complications between the two groups.Postoperative follow-up found that SRC group was more likely to have aortic events than no SRC group(P<0.001).Multivariate COX regression analysis showed that the hazard ratio of aortic end-point events in SRC group was 2.545(95%CI:1.668-3.883,P<0.001).Conclusions The presence of SRC does not affect the occurrence of multiple systemic complications,but can increase the risk of aortic events in the residual aorta after ATAAD.

关 键 词：主动脉疾病 肾疾病 囊性 主动脉夹层 炎症 主动脉瘤 胸 

分 类 号：R543.1[医药卫生—心血管疾病]