负载型咪唑离子液体催化合成2,3-二氢喹唑啉-4(1H)-酮反应研究  

Study on Synthesis of 2,3-dihydroquinazolin-4(1H)-one Catalyzed by Supported Imidazole Ionic Liquid

作　　者：张葶 戎启 胡玉林 Zhang Ting;Rong Qi;Hu Yulin(College of Chemistry and Chemical Engineering,Anshun University,Anshun 561000,China;College of Materials and Chemical Engineering,China Three Gorges University,Yichang 443002,China)

机构地区：[1]安顺学院化学化工学院,贵州安顺561000 [2]三峡大学材料与化工学院,湖北宜昌443002

出　　处：《六盘水师范学院学报》2024年第3期28-37,共10页Journal of Liupanshui Normal University

基　　金：国家自然科学基金项目“离子液体金属纳米复合材料的设计制备及其协同光催化分子氧氧化偶联反应研究”(22268023);安顺学院大学生科研训练计划项目“功能离子液体电解液准固态DSSC设计及性能研究”(asxysrt202320)。

摘　　要：介绍了一种温和条件下催化合成2,3-二氢喹唑啉-4(1H)-酮的方法。该方法以负载型咪唑离子液体Al-MCM-41@ILCeCl_(4)为催化剂,在乙醇溶剂中,催化苯甲醛和2-氨基苯甲酰胺进行反应得到目标化合物,产率高达94%。Al-MCM-41@ILCeCl_(4)催化剂具有制备方法简单、稳定性好、回收利用便捷等优点,符合绿色化学的发展方向,具有良好的应用前景。A type of Al-MCM-41 supported dual imidazolium ionic liquid Al-MCM-41@ILCe Cl_(4) has been synthesized and efficiently used as an catalyst in the one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-one in the condensation of benzaldehyde and anthranilamide.It was shown that the high efficiency with high yield of 94%was achieved under mild conditions.Moreover,the catalyst was stable,very active,robust,and displayed good recyclability without significant loss of catalytic activity after five consecutive cycles during the process.The advantages of Al-MCM-41@ILCe Cl_(4) are simple preparation method,excellent biocompatibility and convenient recycling,which meet the development direction of green chemistry and possess good industrial application prospects.

关 键 词：负载型离子液体 介孔Al-MCM-41 非均相催化 2 3-二氢喹唑啉-4(1H)-酮 可持续性 

分 类 号：X701[环境科学与工程—环境工程] TQ225.52[化学工程—有机化工] TQ426