术后慢性痛发病机制及风险因素研究进展  

Advanees in the mechanism and risk factors of chronic postsurgical pain

作　　者：许学兵 XU Xue-bing(Depurtment of Anaesthe-siology,Honghong University-Shenzhen Hospial,Shenzhen 518053,Guangdong,China)

机构地区：[1]香港大学深圳医院麻醉医学部,广东深圳518053

出　　处：《广东医学》2024年第8期941-945,共5页Guangdong Medical Journal

基　　金：深圳市科技计划项目(JCYJ20210324114607020)。

摘　　要：术后急性疼痛患者有20%~30%的患者会发展成为顽固性慢性痛,统称为术后慢性痛(chronic postsurgical pain,CPSP)。2019年国际疼痛研究协会在第11版国际疾病分类(International Classification of Diseases11,ICD-11)中将CPSP作为一种特定疾病,重新定义了术后慢性痛。CPSP远高于其他术后并发症,会不同程度影响患者的生理和心理,其中有1%的CPSP患者生活质量受到严重影响,经济负担显著增加。本文详细阐述近年来CPSP的发病机制及风险因素研究进展,以期为临床提供指导。Acute postoperative pain progresses to chronic postsurgical pain(CPSP)in 20%-30%of patients,representing a significant clinical challenge.In 2019,the International Association for the Study of Pain(IASP)recognized CPSP as a distinct disease entity in the 11th edition of the International Classification of Diseases(ICD-11).CPSP is more prevalent than other postoperative complications and can significantly impact patients'physical and psychological well-being,with severe impairment in the quality of life for about 1%of patients with CPSP,leading to substantial economic burdens.

关 键 词：慢性疼痛 手术后 发病机制 风险因素 

分 类 号：R614[医药卫生—麻醉学] R765[医药卫生—外科学]