超声引导胸椎旁神经阻滞在胸腔镜肺癌根治术术后镇痛的价值及对认知功能的影响  

The Value of Ultrasound-Guided Thoracic Paravertebral Nerve Block in Postoperative Pain Relief and Its Impact on Cognitive Function After Thoracoscopic Lung Cancer Radical Surgery

作　　者：陈曲敏[1] 高海鹰[1] 蔡东妙[1] CHEN Qu-min;GAO Hai-ying;CAI Dong-miao(Department of Anesthesiology,the First Affiliated Hospital of Xiamen University,Fujian Xiamen 361003)

机构地区：[1]厦门大学附属第一医院麻醉科,福建厦门361003

出　　处：《中国医疗器械信息》2024年第16期19-21,共3页China Medical Device Information

基　　金：福建省自然科学基金项目(面上)(课题名称:Bag3/HK2在丙泊酚引起发育期大脑突触功能障碍中的作用,课题编号:2022J01137)。

摘　　要：目的:探讨超声引导胸椎旁神经阻滞在胸腔镜肺癌根治术术后镇痛的价值及对认知功能的影响。方法:选取胸腔镜下肺癌根治术患者68例,随机分为全麻组及全麻+TPVB组。比较两组术后12、24、48h VAS、MMSE及MoCA量表评分及术后不良反应发生率。结果:全麻+TPVB组术后1d、术后1周VAS评分均低于全麻组(P<0.05);全麻+TPVB组术后1d MMSE评分和MoCA评分均高于全麻组(P<0.05);全麻+TPVB组不良反应发生率为14.3?0%,低于全麻组的36.36%(P<0.05)。结论:超声引导胸椎旁神经阻滞可减轻术后疼痛,改善认知功能,不良反应少,利于术后康复。Objective:To explore the effects of ultrasound-guided thoracic paravertebral nerve block on postoperative analgesia and cognitive function in patients undergoing thoracoscopic radical resection of lung cancer,to determine its value in postoperative analgesia.Methods:68 patients who were about to be treated with thoracoscopic radical lung cancer surgery,were randomly divided into general anesthesia group and general anesthesia+ultrasound-guided thoracic paraspinal nerve block;The VAS,MMSE and MoCA scale scores at 12,24 and 48h after surgery and incidence of anesthetics adverse effects were analysised in both groups.Results:The VAS scores of the general anesthesia+TPVB group were lower than those of the general anesthesia group on postoperative day 1 and week 1(P<0.05);The MMSE score and MoCA score of the general anesthesia+TPVB group were higher than those of the general anesthesia group on postoperative day 1(P<0.05);The incidence of adverse reactions in the general anesthesia+TPVB group was 14.30%,which was lower than the 36.36%in the general anesthesia group(P<0.05).Conclusion:Ultrasound-guided thoracic paraspinal nerve block have less postoperative pain,cognitive improvement,fewer postoperative adverse effects in patients undergoing thoracoscopic radical lung cancer surgery,is beneficial for the recovery of patients.

关 键 词：胸椎旁阻滞 术后镇痛 认知功能 肺癌根治术 超声引导 

分 类 号：R614[医药卫生—麻醉学]