25-羟维生素D、血清钙、血清磷及D-二聚体水平预测产后出血的价值分析  

Analysis on Value of 25-Hydroxyvitamin D,Serum Calcium,Serum Phosphorus and D-Dimer Levels in Predicting Postpartum Hemorrhage

作　　者：景静 Jing Jing(Clinical Laboratory Department,Gaoqing County Maternal and Child Health Care Hospital,Zibo 256300,Shandong Province,China)

机构地区：[1]淄博市高青县妇幼保健院检验科,山东淄博256300

出　　处：《中国社区医师》2024年第21期81-83,共3页Chinese Community Doctors

摘　　要：目的:探讨25-羟维生素D、血清钙、血清磷、D-二聚体水平预测产后出血的价值。方法:选取2020年4月—2022年6月淄博市高青县妇幼保健院妇产科收治的192例分娩产妇作为研究对象,根据是否发生产后出血分为未出血组(n=161)和出血组(n=31)。检测两组25-羟维生素D、血清钙、血清磷、D-二聚体水平。结果:两组血清磷水平比较,差异无统计学意义(P>0.05);出血组D-二聚体水平高于未出血组,血清钙、25-羟维生素D水平低于未出血组(P<0.05)。两组血清磷降低率比较,差异无统计学意义(P>0.05);未出血组D-二聚体升高率、血清钙降低率和25-羟维生素D缺乏率均低于出血组(P<0.05)。D-二聚体、25-羟维生素D、血清钙和血清磷预测产妇产后出血的受试者工作特征曲线下面积(AUC)分别为0.892、0.812、0.721、0.573,D-二聚体、25-羟维生素D和血清钙均有良好的预测价值,血清磷的预测价值一般。结论:25-羟维生素D、血清钙、D-二聚体水平预测产后出血的价值较高。Objective:To explore the value of 25-hydroxyvitamin D,serum calcium,serum phosphorus and D-dimer levels in predicting postpartum hemorrhage.Methods:A total of 192 delivered parturients who were admitted to Gaoqing County Maternal and Child Health Care Hospital from April 2020 to June 2022 were selected as the study subjects.The subjects were divided into non-hemorrhage group(n=161) and hemorrhage group(n=31) according to whether postpartum hemorrhage occurred.The levels of 25-hydroxyvitamin D,serum calcium,serum phosphorus and D-dimer in two groups were detected.Results:There was no significant difference in serum phosphorus levels between the two groups(P>0.05).The levels of D-dimer in the hemorrhage group were higher than those in the non-hemorrhage group,and the levels of serum calcium and 25-hydroxyvitamin D in the hemorrhage group were lower than those in the non-hemorrhage group(P<0.05).There was no significant difference in serum phosphorus decrease rate between the two groups(P>0.05).The D-dimer increase rate,serum calcium decrease rate and 25-hydroxyvitamin D deficiency rate in the hemorrhage group were lower than those in the non-hemorrhage group(P<0.05).The areas under the receiver operating characteristic curve(AUC) of D-dimer,25-hydroxyvitamin D,serum calcium and serum phosphorus in predicting postpartum hemorrhage were 0.892,0.812,0.721 and 0.573,respectively.D-dimer,25-hydroxyvitamin D and serum calcium had good predictive value,while serum phosphorus had moderate predictive value.Conclusion:The levels of25-hydroxyvitamin D,serum calcium and D-dimer have high value in predicting postpartum hemorrhage.

关 键 词：产后出血 25-羟维生素D 血清磷 血清钙 D-二聚体 

分 类 号：R714.461[医药卫生—妇产科学]