蔡氏“育肾周期调治法”治疗排卵障碍性不孕症的临床观察  

Clinical observation of CAI’s“Menstrual cycle regulation therapy for nourishing kidney”in the treatment of ovulatory infertility

作　　者：董丽君 沈萍 DONG Lijun;CHEN Ping

机构地区：[1]上海市黄浦区香山中医医院,上海200020

出　　处：《中医临床研究》2024年第15期112-115,共4页Clinical Journal Of Chinese Medicine

基　　金：上海市黄浦区卫生健康系统扶植项目(2019fzxm07)。

摘　　要：目的:观察蔡氏妇科的“育肾周期调治法”即孕Ⅰ方和孕Ⅱ方治疗排卵障碍性不孕症的临床疗效。方法:将排卵障碍性不孕症患者80例随机分成两组,研究组40例,服用孕Ⅰ方和孕Ⅱ方;对照组40例,服用中成药河车大造胶囊,1个月经周期为一个疗程,连续治疗6个疗程。观察患者的排卵率、妊娠率、血清激素水平的变化,对比观察两组的疗效。结果:①治疗6个月经周期后,研究组的总有效率为87.5%,对照组总有效率为77.5%,研究组的总有效率高于对照组,差异有统计学意义(P<0.05);②两组患者治疗后血清卵泡刺激素(Follicle Stimulating Hormone,FSH)、促黄体生成素(Luteinizing Hormone,LH)水平较治疗前有下降趋势,但差异没有统计学意义(P>0.05)。雌二醇(Estrogen,E2)水平较治疗前明显升高,差异均有统计学意义(P<0.05),但两组之间差异无统计学意义。③通过彩超监测发现,治疗后两组优势卵泡直径均较治疗前增大,差异均有统计学意义(P<0.05),且研究组优于对照组,差异有统计学意义(P<0.05)。两组治疗后子宫内膜厚度大于治疗前,差异均有统计学意义(P<0.05),且研究组优于对照组,差异有统计学意义(P<0.05)。结论:蔡氏育肾周期调治法治疗排卵障碍性不孕症的临床疗效良好,能够改善患者的FSH、LH、E2等生殖激素水平,改善子宫内膜厚度和卵泡直径,提高妊娠和排卵率。Objective:To observe the clinical effect of CAI’s gynecological“Menstrual cycle regulation therapy for nourishing kidney’,i.e,Pregnancy Formula I and Pregnancy Formula II,in the treatment of ovulatory infertility.Methods:A total of 80 patients with anovulatory infertility were randomly divided into two groups.Forty patients in the study group were given Pregnancy Formula I and Pregnancy Formula II.Forty cases in the control group were treated with Chinese patent medicine Heche Dazao capsules(河车大造胶囊).One menstrual cycle was a course of treatment,and 6 courses were erformed continuously.The curative effects in the two groups were compared through the changes of ovulation rate,pregnancy rate and serum hormone level.Results:①After 6 menstrual cycles of treatment,the total effective rate in the study group was 87.5%,and that in the control group was 77.5%,the total effective rate in the study group was higher than the control group,the difference was statistically significant(P<0.05).②The serum FSH and LH levels in the two groups after treatment had a downward trend compared with those before treatment,but the difference was not statistically significant(P>0.05).The level of E2 was significantly higher than that before treatment,the difference was statistically significant(P<0.05),but there was no statistically significant difference between the two groups.③Color ultrasound monitoring showed that the dominant follicle diameter in both groups were increased after treatment compared with that before treatment,the difference was statistically significant(P<0.05);the study group was better than the control group,and the difference was statistically significant(P<0.05).The endometrial thickness in the two groups after treatment was greater than that before treatment,the difference was statistically significant(P<0.05);the study group was better than the control group,and the difference was statistically significant(P<0.05).Conclusion:CAI’s“Menstrual cycle regulation therapy for nourishing kidney

关 键 词：不孕症 排卵障碍 蔡氏妇科 育肾周期调治法 

分 类 号：R271.14[医药卫生—中医妇科学]