自拟槿柏洗方外洗联合萘替芬酮康唑乳膏治疗小儿头癣美学效果观察  

Aesthetic Effect of Self-made Jinbai Washing Prescription Combined With Anti-fungus Ointment in the Treatment of Children with Tinea Capitis

作　　者：姜桂仙[1] 杨晓丽[1] 任媛媛 宫安明[1] JIANG Guixian;YANG Xiaoli;REN Yuanyuan;GONG Anming(Department of Dermatology,Qinhuangdao Hospital of Traditional Chinese Medicine,Qinhuangdao 066000,Hebei,China)

机构地区：[1]秦皇岛市中医医院皮肤科,河北秦皇岛066000

出　　处：《中国美容医学》2024年第9期70-73,共4页Chinese Journal of Aesthetic Medicine

基　　金：秦皇岛市科技局2023年度市级自筹项目(编号:202301A070)。

摘　　要：目的:研究自拟槿柏洗方外洗联合萘替芬酮康唑乳膏治疗小儿头癣的美学效果。方法:选取2021年5月-2023年4月在秦皇岛市中医医院中医皮肤科收治的82例头癣患儿,根据随机数表法将其分为联合组和对照组,各41例。对照组单纯采用抗真菌药膏外涂治疗,2次/天,持续治疗4周;联合组在对照组基础上联合自拟槿柏洗方外洗治疗,2次/天,持续治疗4周。观察比较两组患儿治疗开始时、结束时及停药后4周患儿头部的靶皮损(皮损面积最大处)状况[皮损面积、红斑、鳞屑(脓疱/黄痂)、瘙痒]评分和头皮严重指数(PSSI)评分,患儿治疗结束时的疗效,患儿治疗结束4周后复发情况和家长美观满意度,患儿治疗期间的不良反应发生情况。结果:联合组患儿总有效率高于对照组(P<0.05);治疗后,两组患儿靶皮损状况评分和PSSI评分均低于治疗前,且联合组患儿靶皮损状况评分和PSSI评分均低于对照组(P<0.05)。治疗期间,联合组患儿总不良反应发生率低于对照组(P<0.05);治疗结束4周后,联合组家长美观满意度高于对照组(P<0.05);联合组复发率与对照组比较,差异无统计学意义(P>0.05)。结论:相比于单纯使用抗真菌药膏外涂治疗小儿头癣,自拟槿柏洗方外洗联合萘替芬酮康唑乳膏对头皮的损伤程度更小,疗效更佳,家长美观满意度更高,治疗后不良反应发生率更低。Objective To study the aesthetic effect of self-made Jinbai washing prescription combined with anti-fungus ointment in the treatment of children with tinea capitis.Methods A total of 82 children with tinea capitis admitted to TCM dermatology department of Qinhuangdao Hospital of Traditional Chinese Medicine were enrolled between May 2021 and April 2023.According to random number table method,they were divided into combination group and control group,41 cases in each group.The control group was treated with anti-fungus ointment,while combination group was additionally treated with selfmade Jinbai washing prescription.All were treated twice/d for 4 weeks.The scores of skin lesions[lesion area,erythema,squame(pustules/scutulum),pruritis]in head target skin(at the place with the largest skin lesion area)and psoriasis scalp severity index(PSSI)at the beginning of treatment,the end of treatment and 4 weeks after withdrawal,curative effect after treatment,recurrence and parents'aesthetics satisfaction at 4 weeks after treatment,and the occurrence of adverse reactions during treatment in the two groups were observed and compared.Results The total response rate of combination group was higher than that of control group(P<0.05).After treatment,scores of skin lesions of target skin and PSSI were decreased in both groups,which were lower in combination group than control group(P<0.05).During treatment,total incidence of adverse reactions in combination group was lower than that in control group(P<0.05).At 4 weeks after treatment,aesthetics satisfaction of parents in combination group was higher than that in control group,and scores of skin lesions of target skin and PSSI were lower than those in control group(P<0.05).There was no significant difference in recurrence rate between the two groups(P>0.05).Conclusion Compared with anti-fungus ointment alone,self-made Jinbai washing prescription combined with anti-fungus ointment has less scalp injury,better curative effect,higher parents’aesthetics satisfaction and lower incide

关 键 词：自拟槿柏洗方 抗真菌药膏 头癣 美学效果 满意度 

分 类 号：R756.1[医药卫生—皮肤病学与性病学]