膝骨关节炎疼痛领域热点与前沿的可视化分析  

Visual analysis of hotspots and frontiers in knee osteoarthritis pain field

作　　者：赵盾 祁令臣 徐金凡 邵敏[2] Zhao Dun;Qi Lingchen;Xu Jinfan;Shao Min(Guangzhou University of Chinese Medicine,Guangzhou 510000,Guangdong Province,China;Shunde Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510000,Guangdong Province,China)

机构地区：[1]广州中医药大学,广东省广州市510000 [2]广州中医药大学顺德医院,广东省广州市510000

出　　处：《中国组织工程研究》2025年第15期3280-3289,共10页Chinese Journal of Tissue Engineering Research

摘　　要：背景:疼痛是膝骨关节炎的主要症状,严重影响老年患者的生活质量。膝骨关节炎疼痛机制复杂,涉及多组织、多学科,需要可视化分析了解其主要内容与研究热点。目的:运用文献计量学可视化软件分析归纳膝骨关节炎疼痛领域的前沿内容和研究热点。方法:从Web of Science核心合集(Web of Science Core Collection,WoSCC)中检索2014-2024年膝骨关节炎疼痛领域的相关文献,运用Citespace、VOSviewer和Bibliometrix R-package三个可视化软件进行文献计量与可视化分析。结果与结论:①膝骨关节炎疼痛研究的发文量呈现逐年递增的趋势;②美国、中国、澳大利亚是该领域10年内发文量排名前三的国家;波士顿大学、悉尼大学、弗洛里达大学是发文量前三的科研机构;《OSTEOARTHRITIS AND CARTILAGE》是出版该领域文献最多的期刊,《PAIN》则是该领域被引次数最多的期刊;发文量最多的作者是Fillingim Roger B,该领域的核心作者之间已经建立了一些稳定的团队,但国际性合作尚有欠缺;③膝骨关节炎疼痛患者的日常管理(运动、心理、智能管理)、疼痛的炎症机制、蛋白组学、联合用药、中枢敏化和疼痛调节是膝骨关节炎疼痛研究的重点内容;人工智能辅助、体外冲击波疗法、射频消融术、神经冷冻术、关节腔内注射血液或细胞制剂可能是该领域的研究前沿。BACKGROUND:Pain is the main symptom of knee osteoarthritis,which seriously affects the quality of life of elderly patients.The pain mechanism of knee osteoarthritis is complex and involves multi-tissue and multi-discipline.Visual analysis is needed to understand its cutting-edge content and research hotspots.OBJECTIVE:To analyze and summarize the cutting-edge content and research hotspot in knee osteoarthritis pain field using bibliometrics visualization software.METHODS:Literatures related to knee osteoarthritis pain from 2014 to 2024 were retrieved from Web of Science Core Collection(WoSCC).Three visualization software,Citespace,VOSviewer,and Bibliometrix R-Package were used for bibliometric and visual analysis.RESULTS AND CONCLUSION:(1)The number of articles on knee osteoarthritis pain research is increasing year by year.(2)The United States,China,and Australia were the top three countries in the number of publications in this field in 10 years.Boston University,University of Sydney,and University of Florida are the top three research institutions.OSTEOARTHRITIS AND CARTILAGE has published the most research articles in this field,and PAIN has been the most cited journal in this field.The author with the most published articles is Fillingim Roger B.The active authors in this field have formed a number of stable research teams among themselves,but there is a lack of international cooperation.(3)Daily management(motor,psychological,and intelligent management),inflammatory mechanism of pain,proteomics,combination medication,central sensitization,and pain regulation of knee osteoarthritis pain patients are the key contents of knee osteoarthritis pain research.Artificial intelligence assistance,extracorporeal shock wave therapy,radiofrequency ablation,nerve cryotherapy,intra-articular injection of blood or cell preparations may be the research frontiers in this field.

关 键 词：VOSviewer软件 Citespace软件 Bibliometrix R-package 文献计量学 炎症因子 体外冲击波疗法 疼痛管理 神经阻滞 蛋白组学 

分 类 号：R459.9[医药卫生—治疗学] R318[医药卫生—临床医学] R684