Assessing Coarctation of the Aorta With Fetal Heart Quantification Technology  

作　　者：Jiaojiao Yang Fang Tan Yuqin Shen Yuan Zhao Yan Xia Sihan Fan Xueqin Ji 

机构地区：[1]Department of Obstetrics and Gynecology Center,General Hospital of Ningxia Medical University,Yinchuan,Ningxia 750003,China [2]Ultrasound Medicine Department,Xian Yang Central Hospital,Xianyang,Shaanxi 712099,China [3]Ultrasound Medicine Department,Peking University First Hospital Ningxia Women’s and Children's Hospital(Ningxia Hui Autonomous Region Maternal and Child Health Hospital),Yinchuan,Ningxia 750002,China [4]Ningxia Medical University,Yinchuan,Ningxia 750004,China

出　　处：《Maternal-Fetal Medicine》2024年第3期147-155,共9页母胎医学杂志（英文）

基　　金：funded by the Ningxia Natural Science Foundation(grant ID.2022A1467).

摘　　要：Objective:To use fetal heart quantification(fetal HQ)technology to compare the coarctation of the aorta(CoA)and normal fetal heart structure and systolic function and to assess whether there are abnormalities in the fetal heart structure and systolic function associated with CoA.Methods:This prospective cohort study was conducted from May 2020 to December 2022 and involved 18–40-week-old singleton pregnancies and 30 fetuses diagnosed with CoA using fetal echocardiography at the General Hospital of Ningxia Medical University and Peking University First Hospital Ningxia Women’s andChildren’s Hospital,China.The control group contained 60 normal fetuses.The following parameters were recorded and analyzed statistically:four-chamber view(4CV)end-diastolic long diameter,4CV epicardial–contralateral epicardial transverse maximum diameter,4CV global sphericity index(GSI),left ventricular(LV)and right ventricular(RV)24-segment end-diastolic diameter(EDD),24-segment sphericity index(SI),LV-fractional area change(LV-FAC),LV-longitudinal strain(LV-LS),RV-fractional area change(RV-FAC),RV-longitudinal strain(RV-LS),and LV and RV 24-segment transverse fractional shortening(FS).Measurement data were compared between the two groups using an independent sample t test,with P<0.05 indicating statistically significant differences.Moreover,the correlation between gestational age and GSI,LV-FAC,LV-LS,RV-FAC,and RV-LS was assessed.Results:Within and between observer comparisons of the parameters associated with major cardiac function revealed an intragroup correlation coefficient of>0.9,indicating high consistency,and a coefficient of variable of<1%,indicating low variability.Correlation analysis revealed no obvious correlation between gestational age and GSI,LV-FAC,LV-LS,RV-FAC,and RV-LS.A comparison of the fourchamber morphological structural parameters of the hearts in the two groups revealed that when compared with the control group,the 4CV end-diastolic long diameter was shortened in fetuses in the CoA group and the epicard

关 键 词：Fetal heart Quantitative analysis technology Fetal HQ software Coarctation of the aorta Spherical index Systolic function 

分 类 号：R714.5[医药卫生—妇产科学]